Ionic liquids as media for nucleophilic fluorination

被引：44
作者：
Murray, CB
Sandford, G
Korn, SR
机构：
[1] Univ Durham, Dept Chem, Durham DH1 3LE, England
[2] Avecia, Huddersfield HD2 1GA, W Yorkshire, England
来源：
JOURNAL OF FLUORINE CHEMISTRY | 2003年 / 123卷 / 01期
关键词：
ionic liquids; fluoride ion; nucleophilic fluorination; green chemistry;
D O I：
10.1016/S0022-1139(03)00132-5
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The use of Room Temperature Ionic Liquids (RTILs) for a variety of halogen exchange (Halex) fluorination processes using alkali metal fluorides is assessed. Whilst fluorination of a range of halogenated substrates is possible in good yield, the utility of RTILs as reusable, inert media for such reactions is limited by the gradual decomposition of the RTIL in the presence of highly basic fluoride ion. (C) 2003 Elsevier Science B.V. All rights reserved.
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页码：81 / 84
页数：4
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