The Immunomodulatory Role of Vitamin D in Respiratory Diseases

被引：6
作者：
Pulvirenti, Giulio [1 ]
Parisi, Giuseppe Fabio [1 ]
Manti, Sara [1 ,2 ]
Licari, Amelia [3 ]
del Giudice, Michele Miraglia [4 ]
Salpietro, Carmelo [2 ]
Marseglia, Gian Luigi [3 ]
Leonardi, Salvatore [1 ]
机构：
[1] Univ Catania, Dept Clin & Expt Med, Catania, Italy
[2] Univ Messina, Dept Pediat, Messina, Italy
[3] Univ Pavia, Dept Pediat, Fdn IRCCS Policlin San Matteo, Pavia, Italy
[4] Univ Campania Luigi Vanvitelli, Dept Woman Child & Gen & Specialist Surg, Naples, Italy
来源：
CURRENT RESPIRATORY MEDICINE REVIEWS | 2019年 / 15卷 / 03期
关键词：
Asthma; cystic fibrosis; recurrent respiratory infections; respiratory disease; Vitamin D; immunomodulatory; CHRONIC RHINOSINUSITIS; D DEFICIENCY; D SUPPLEMENTATION; CYSTIC-FIBROSIS; DOUBLE-BLIND; ASTHMA EXACERBATIONS; TAIWANESE PATIENTS; CHILDHOOD ASTHMA; CONTROLLED-TRIAL; D REPLACEMENT;
D O I：
10.2174/1573398X15666191114144230
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The growing interest in the new role of vitamin D, particularly as an immunomodulatory factor, has spurred basic research and the development of clinical trials to better understand the influence of supplementation on various diseases. Vitamin D is an important nutrient factor in human health due to its role in calcium metabolism regulation, cellular growth, differentiation and its fundamental discovered activity in immune functions. It has influenced different diseases, particularly inflammatory and autoimmune diseases, through immune response regulation, modulating innate and adaptive immunity. The aim of this review was to explore the role of vitamin D in the main respiratory diseases in children such as asthma, chronic rhinosinusitis, cystic fibrosis and recurrent respiratory infections.
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收藏
页码：238 / 245
页数：8
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