Survival after out-of-hospital cardiac arrest in Europe - Results of the EuReCa TWO study

被引:609
作者
Graesner, Jan-Thorsten [1 ,2 ]
Wnent, Jan [1 ,2 ,3 ]
Herlitz, Johan [4 ]
Perkins, Gavin D. [5 ,6 ]
Lefering, Rolf [7 ]
Tjelmeland, Ingvild [1 ,8 ]
Koster, Rudolph W. [9 ]
Masterson, Siobhan [10 ]
Rossell-Ortiz, Fernando [11 ]
Maurer, Holger [12 ]
Boettiger, Bernd W. [13 ,18 ]
Moertl, Maximilian [14 ]
Mols, Pierre [15 ]
Alihodic, Hajriz [16 ,17 ]
Hadibegovic, Irzal [18 ]
Ioannides, Marios [19 ]
Truhlar, Anatolij [20 ,21 ]
Wissenberg, Mads [22 ]
Salo, Ari [23 ,24 ]
Escutnaire, Josephine [25 ]
Nikolaou, Nikolaos [26 ,27 ]
Nagy, Eniko [28 ]
Jonsson, Bergthor Steinn [29 ]
Wright, Peter [30 ,31 ]
Semeraro, Federico [32 ]
Clarens, Carlo [33 ]
Beesems, Steffie [34 ]
Cebula, Grzegorz [35 ]
Correia, Vitor H. [36 ]
Cimpoesu, Diana [37 ]
Raffay, Violetta [38 ]
Trenkler, Stefan [39 ]
Markota, Andrej [10 ,40 ,41 ]
Stroemsoee, Anneli [42 ,43 ,44 ]
Burkart, Roman [45 ]
Booth, Scott [5 ]
Bossaert, Leo [46 ,47 ]
机构
[1] Univ Hosp Schleswig Holstein, Inst Emergency Med, Kiel, Germany
[2] Univ Hosp Schleswig Holstein, Dept Anesthesiol & Intens Care Med, Kiel, Germany
[3] Univ Namibia, Sch Med, Windhoek, Namibia
[4] Univ Boras, Fac Caring Sci Work Life & Social Welf, Prehospen Ctr Prehosp Res, Boras, Sweden
[5] Univ Warwick, Warwick Med Sch, Warwick Clin Trials Unit, Coventry, W Midlands, England
[6] Univ Hosp Birmingham NHS Fdn Trust, Birmingham, W Midlands, England
[7] Univ Witten Herdecke, Abt Stat & Registerforsch, IFOM, Witten, Germany
[8] Oslo Univ Hosp, Div Prehosp Serv, Oslo, Norway
[9] Locat Acad Med Ctr, Amsterdam UMC, Dept Cardiol, Amsterdam, Netherlands
[10] Natl Univ Ireland Galway, HSE Natl Ambulance Serv, Discipline Gen Practice, Galway, Ireland
[11] Empresa Publ Emergencias Sanitarias Andalucia, Malaga, Spain
[12] Univ Hosp Schleswig Holstein, Dept Anesthesiol & Intens Care Med, Lubeck, Germany
[13] Univ Hosp Cologne, Dept Anaesthesiol & Intens Care Med, Cologne, Germany
[14] Univ Klin Innsbruck, Dept Anaesthesia & Intens Care, Innsbruck, Austria
[15] Univ Libre Bruxelles, CHU St Pierre, Brussels, Belgium
[16] Univ Tuzla, Publ Inst Hlth Ctr Dr Mustafa Ehovic, Emergency Med Serv, Tuzla, Bosnia & Herceg
[17] Univ Tuzla, Fac Med, Tuzla, Bosnia & Herceg
[18] Josip Juraj Strossmayer Univ Osijek, Fac Dent Med & Hlth, Univ Hosp Dubrava Zagreb, Osijek, Croatia
[19] Nicosia Gen Hosp, Nicosia, Cyprus
[20] Emergency Med Serv Hradec Kralove Reg, Hradec Kralove, Czech Republic
[21] Univ Hosp Hradec Kralove, Dept Anaesthesiol & Intens Care Med, Hradec Kralove, Czech Republic
[22] Univ Copenhagen, Emergency Med Serv Copenhagen, Copenhagen, Denmark
[23] Helsinki Univ Hosp, Dept Emergency Med, Emergency Med Serv, Helsinki, Finland
[24] Univ Helsinki, Helsinki, Finland
[25] Univ Lille, CHU Lille, EA 2694, Sante Publ Epidemiol & Qual Soins, F-59000 Lille, France
[26] Konstantopouleio Gen Hosp, Dept Cardiol, Athens, Greece
[27] Konstantopouleio Gen Hosp, ICCU, Athens, Greece
[28] Univ Szeged, Emergency Dept, Hungarian Resuscitat Council, Szeged, Hungary
[29] Mayo Clin, Dept Emergency Med, Coll Med, Rochester, MN USA
[30] HSE Natl Ambulance Serv, Galway, Ireland
[31] Natl Univ Ireland Galway, Galway, Ireland
[32] Osped Maggiore Bologna, Dept Anaesthesia Intens Care & Emergency Med Serv, Bologna, Italy
[33] Luxembourg Resuscitat Council, Luxembourg, Luxembourg
[34] Amsterdam UMC, Acad Med Ctr, Ctr Heart, Dept Cardiol, Amsterdam, Netherlands
[35] Jagiellonian Univ, Coll Med, Fac Med, Dept Med Educ, Krakow, Poland
[36] Emergency Med Serv SEMER EMIR, Funchal, Portugal
[37] Univ Med & Pharm Gr T Popa Iasi, Emergency Cty Hosp Sf Spiridon, Emergency Dept, Iasi, Romania
[38] Serbian Resuscitat Council, Novi Sad, Serbia
[39] Safarik Univ, L Pasteur Univ Hosp, Dept Anaesthesiol & Intens Med, Fac Med, Kosice, Slovakia
[40] Univ Med Ctr Maribor, Med Intens Care Unit, Maribor, Slovenia
[41] Slovenian Resuscitat Council, Slovenian Soc Emergency Med, Ljubljana, Slovenia
[42] Cty Council Dalarna, Dept Prehosp Care, Falun, Sweden
[43] Ctr Clin Res, Falun, Dalarna, Sweden
[44] Dalarna Univ, Sch Educ Hlth & Social Studies, Falun, Sweden
[45] Interassoc Rescue Serv, Bern, Switzerland
[46] Univ Antwerp, Antwerp, Belgium
[47] ERC, Niel, Belgium
关键词
Out-of-hospital cardiac arrest; European registry of cardiac arrest; Bystander CPR; Outcome after OHCA; Resuscitation; VENTRICULAR-FIBRILLATION; RESUSCITATION; INTERVENTION; ASSOCIATION; MANAGEMENT; BYSTANDER; OUTCOMES; REGISTRY;
D O I
10.1016/j.resuscitation.2019.12.042
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. Methods: This prospective, multicentre study involved the collection of registry-based data over a three-month period (1st October 2017 to 31st December 2017). The core study dataset complied with the Utstein-style. Primary outcomes were return of spontaneous circulation (ROSC) and survival to hospital admission. Secondary outcome was survival to hospital discharge. Results: All 28 countries provided data, covering a total population of 178,879,118. A total of 37,054 OHCA were confirmed, with CPR being started in 25,171 cases. The bystander cardiopulmonary resuscitation (CPR) rate ranged from 13% to 82% between countries (average: 58%). In one third of cases (33%) ROSC was achieved and 8% of patients were discharged from hospital alive. Survival to hospital discharge was higher in patients when a bystander performed CPR with ventilations, compared to compression-only CPR (14% vs. 8% respectively). Conclusion: In addition to increasing our understanding of the role of bystander CPR within Europe, EuReCa TWO has confirmed large variation in OHCA incidence, characteristics and outcome, and highlighted the extent to which OHCA is a public health burden across Europe. Unexplained variation remains and the EuReCa network has a continuing role to play in improving the quality management of resuscitation.
引用
收藏
页码:218 / 226
页数:9
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