Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of urothelial cancer

被引：28

作者：

Galsky, Matthew D. ^{[1
]}

Balar, Arjun, V ^{[2
]}

Black, Peter C. ^{[3
]}

Campbell, Matthew T. ^{[4
]}

Dykstra, Gail S. ^{[5
,6
]}

Grivas, Petros ^{[7
,8
]}

Gupta, Shilpa ^{[9
]}

Hoimes, Christoper J. ^{[10
]}

Lopez, Lidia P. ^{[11
]}

Meeks, Joshua J. ^{[12
,13
]}

Plimack, Elizabeth R. ^{[14
]}

Rosenberg, Jonathan E. ^{[15
,16
]}

Shore, Neal ^{[17
]}

Steinberg, Gary D. ^{[18
,19
]}

Kamat, Ashish M. ^{[20
]}

机构：

[1] Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA

[2] NYU, Perlmutter Canc Ctr, Langone Med Ctr, New York, NY USA

[3] Univ British Columbia, Dept Urol Sci, Vancouver, BC, Canada

[4] Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, Div Canc Med, Houston, TX 77030 USA

[5] Bladder Canc Advocacy Network BCAN, Bethesda, MD USA

[6] Dykstra Res, Washington, DC USA

[7] Univ Washington, Dept Med, Div Oncol, Seattle, WA 98195 USA

[8] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, 1124 Columbia St, Seattle, WA 98104 USA

[9] Cleveland Clin, Dept Hematol & Oncol, Taussig Canc Inst, Cleveland, OH 44106 USA

[10] Duke Univ, Dept Med, Duke Canc Inst, Durham, NC USA

[11] Univ Calif Los Angeles, Dept Med, Div Hematol Oncol, Los Angeles, CA 90024 USA

[12] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA

[13] Jesse Brown VA Med Ctr, Chicago, IL USA

[14] Fox Chase Canc Ctr, Dept Hematol Oncol, 7701 Burholme Ave, Philadelphia, PA 19111 USA

[15] Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USA

[16] Weill Cornell Med Coll, Dept Med, New York, NY USA

[17] Carolina Urol Res Ctr, Myrtle Beach, SC USA

[18] NYU Langone Med Ctr, Dept Urol, New York, NY USA

[19] NYU Langone Med Ctr, Perlmutter Canc Ctr, New York, NY USA

[20] Univ Texas MD Anderson Canc Ctr, Dept Urol, Div Surg, Houston, TX 77030 USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2021年 / 9卷 / 07期

关键词：

antineoplastic protocols; guidelines as topic; immunotherapy; urinary bladder neoplasms; urologic neoplasms; BACILLUS-CALMETTE-GUERIN; INVASIVE BLADDER-CANCER; QUALITY-OF-LIFE; CISPLATIN-INELIGIBLE PATIENTS; T1 PAPILLARY CARCINOMA; HIGH-RISK TA; PHASE-III; ENFORTUMAB VEDOTIN; INTRAVESICAL BCG; DOUBLE-BLIND;

D O I：

10.1136/jitc-2021-002552

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A number of immunotherapies have been developed and adopted for the treatment of urothelial cancer (encompassing cancers arising from the bladder, urethra, or renal pelvis). For these immunotherapies to positively impact patient outcomes, optimal selection of agents and treatment scheduling, especially in conjunction with existing treatment paradigms, is paramount. Immunotherapies also warrant specific and unique considerations regarding patient management, emphasizing both the prompt identification and treatment of potential toxicities. In order to address these issues, the Society for Immunotherapy of Cancer (SITC) convened a panel of experts in the field of immunotherapy for urothelial cancer. The expert panel developed this clinical practice guideline (CPG) to inform healthcare professionals on important aspects of immunotherapeutic treatment for urothelial cancer, including diagnostic testing, treatment planning, immune-related adverse events (irAEs), and patient quality of life (QOL) considerations. The evidence- and consensus-based recommendations in this CPG are intended to give guidance to cancer care providers treating patients with urothelial cancer.

引用

页数：21

共 154 条

[51] Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up [J].

Fradet, Y. ;

Bellmunt, J. ;

Vaughn, D. J. ;

Lee, J. L. ;

Fong, L. ;

Vogelzang, N. J. ;

Climent, M. A. ;

Petrylak, D. P. ;

Choueiri, T. K. ;

Necchi, A. ;

Gerritsen, W. ;

Gurney, H. ;

Quinn, D., I ;

Culine, S. ;

Sternberg, C. N. ;

Nam, K. ;

Frenkl, T. L. ;

Perini, R. F. ;

de Wit, R. ;

Bajorin, D. F. .

ANNALS OF ONCOLOGY, 2019, 30 (06) :970-976

[52] MMR deficiency in urothelial carcinoma of the bladder presents with temporal and spatial homogeneity throughout the tumor mass [J].

Fraune, Christoph ;

Simon, Ronald ;

Hube-Magg, Claudia ;

Makrypidi-Fraune, Georgia ;

Kaehler, Christian ;

Kluth, Martina ;

Hoeflmayer, Doris ;

Buescheck, Franziska ;

Dum, David ;

Luebke, Andreas M. ;

Burandt, Eike ;

Clauditz, Till Sebastian ;

Wilczak, Waldemar ;

Sauter, Guido ;

Steurer, Stefan .

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2020, 38 (05) :488-495

[53] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death [J].

Galluzzi, Lorenzo ;

Vitale, Ilio ;

Warren, Sarah ;

Adjemian, Sandy ;

Agostinis, Patrizia ;

Buque Martinez, Aitziber ;

Chan, Timothy A. ;

Coukos, George ;

Demaria, Sandra ;

Deutsch, Eric ;

Draganov, Dobrin ;

Edelson, Richard L. ;

Formenti, Silvia C. ;

Fucikova, Jitka ;

Gabriele, Lucia ;

Gaipl, Udo S. ;

Gameiro, Sofia R. ;

Garg, Abhishek D. ;

Golden, Encouse ;

Han, Jian ;

Harrington, Kevin J. ;

Hemminki, Akseli ;

Hodge, James W. ;

Hossain, Dewan Md Sakib ;

Illidge, Tim ;

Karin, Michael ;

Kaufman, Howard L. ;

Kepp, Oliver ;

Kroemer, Guido ;

Lasarte, Juan Jose ;

Loi, Sherene ;

Lotze, Michael T. ;

Manic, Gwenola ;

Merghoub, Taha ;

Melcher, Alan A. ;

Mossman, Karen L. ;

Prosper, Felipe ;

Rekdal, Oystein ;

Rescigno, Maria ;

Riganti, Chiara ;

Sistigu, Antonella ;

Smyth, Mark J. ;

Spisek, Radek ;

Stagg, John ;

Strauss, Bryan E. ;

Tang, Daolin ;

Tatsuno, Kazuki ;

van Gool, Stefaan W. ;

Vandenabeele, Peter ;

Yamazaki, Takahiro .

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 (01)

[54] Immunogenic cell death in cancer and infectious disease [J].

Galluzzi, Lorenzo ;

Buque, Aitziber ;

Kepp, Oliver ;

Zitvogel, Laurence ;

Kroemer, Guido .

NATURE REVIEWS IMMUNOLOGY, 2017, 17 (02) :97-111

[55]

Galsky MD, 2020, J CLIN ONCOL, V38

[56]

Galsky MD, 2013, J CLIN ONCOL, V31

[57] Nivolumab in Patients with Advanced Platinum-resistant Urothelial Carcinoma: Efficacy, Safety, and Biomarker Analyses with Extended Follow-up from CheckMate 275 [J].

Galsky, Matthew D. ;

Saci, Abdel ;

Szabo, Peter M. ;

Han, G. Celine ;

Grossfeld, Gary ;

Collette, Sandra ;

Siefker-Radtke, Arlene ;

Necchi, Andrea ;

Sharma, Padmanee .

CLINICAL CANCER RESEARCH, 2020, 26 (19) :5120-5128

[58] Atezolizumab with or without chemotherapy in metastatic urothelial cancer (IMvigor130): a multicentre, randomised, placebo-controlled phase 3 trial [J].

Galsky, Matthew D. ;

Arranz Arija, Jose Angel ;

Bamias, Aristotelis ;

Davis, Ian D. ;

De Santis, Maria ;

Kikuchi, Eiji ;

Garcia-del-Muro, Xavier ;

De Giorgi, Ugo ;

Mencinger, Marina ;

Izumi, Kouji ;

Panni, Stefano ;

Gumus, Mahmut ;

Ozguroglu, Mustafa ;

Kalebasty, Arash Rezazadeh ;

Park, Se Hoon ;

Alekseev, Boris ;

Schutz, Fabio A. ;

Li, Jian-Ri ;

Ye, Dingwei ;

Vogelzang, Nicholas J. ;

Bernhard, Sandrine ;

Tayama, Darren ;

Mariathasan, Sanjeev ;

Mecke, Almut ;

Thastrom, AnnChristine ;

Grande, Enrique .

LANCET, 2020, 395 (10236) :1547-1557

[59] Randomized Double-Blind Phase II Study of Maintenance Pembrolizumab Versus Placebo After First-Line Chemotherapy in Patients With Metastatic Urothelial Cancer [J].

Galsky, Matthew D. ;

Mortazavi, Amir ;

Milowsky, Matthew, I ;

George, Saby ;

Gupta, Sumati ;

Fleming, Mark T. ;

Dang, Long H. ;

Geynisman, Daniel M. ;

Walling, Radhika ;

Alter, Robert S. ;

Kassar, Mohamad ;

Wang, Jue ;

Gupta, Shilpa ;

Davis, Nancy ;

Picus, Joel ;

Philips, George ;

Quinn, David, I ;

Haines, G. Kenneth, III ;

Hahn, Noah M. ;

Zhao, Qianqian ;

Yu, Menggang ;

Pal, Sumanta K. .

JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (16) :1797-+

[60]

Galsky MD., 2021, GEN CANC S AM SOC CL

← 1 2 3 4 5 6 7 8 9 10 →