Reflex Seizures Triggered by Diaper Change in Dravet Syndrome

被引：7

作者：

Subki, Ahmed H. ^{[1
]}

Alasmari, Aishah S. ^{[1
]}

Jan, Fadi M. ^{[1
]}

Moria, Feras A. ^{[1
]}

Jan, Mohammed M. ^{[1
]}

机构：

[1] King Abdulaziz Univ, Dept Pediat, Jeddah, Saudi Arabia

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 2016年 / 43卷 / 04期

关键词：

Epilepsy; -; pediatric; Reflex; Dravet; Syndrome; Diaper; Seizures; Trigger; SEVERE MYOCLONIC EPILEPSY; MANAGEMENT;

D O I：

10.1017/cjn.2015.394

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dravet syndrome (DS) is a severe epilepsy syndrome characterized by early onset of multiple types of seizures. We report the first case of reflex seizures triggered by diaper change in a girl at 9 months old and 2 years old with a mutation in the SCN1A gene causing DS. Reflex seizures have been reported in patients with DS provoked by increased body temperature or visual stimulation. The case we report widens the spectrum of triggers causing reflex seizures in children with DS. Cortical hyperexcitability resulting from the genetic defect explains the tendency to experience such reflex seizures.

引用

页码：585 / 587

页数：3

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