Spatiotemporal distribution of antimicrobial resistant organisms in different water environments in urban and rural settings of Bangladesh

被引：24

作者：

Asaduzzaman, Muhammad ^{[1
,2
,8
]}

Rousham, Emily ^{[3
]}

Unicomb, Leanne ^{[4
]}

Islam, Md. Rayhanul ^{[2
]}

Amin, Mohammed Badrul ^{[2
]}

Rahman, Mahdia ^{[2
]}

Hossain, Muhammed Iqbal ^{[2
]}

Mahmud, Zahid Hayat ^{[2
]}

Szegner, Mark ^{[5
]}

Wood, Paul ^{[5
]}

Islam, Mohammad Aminul ^{[2
,6
,7
]}

机构：

[1] Univ Oslo, Inst Hlth & Soc, Fac Med, Dept Community Med & Global Hlth, Oslo, Norway

[2] Int Ctr Diarrhoeal Dis Res, Lab Sci & Serv Div, Food Safety & One Hlth Lab, Icddr, Dhaka 1212, Bangladesh

[3] Loughborough Univ, Ctr Global Hlth & Human Dev, Sch Sport Exercise & Hlth Sci, Loughborough, England

[4] Int Ctr Diarrhoeal Dis Res, Infect Dis Div, Environm Intervent Unit, icddr b, Dhaka 1212, Bangladesh

[5] Loughborough Univ, Sch Social Sci & Humanities, Geog & Environm, Loughborough, England

[6] Washington State Univ, Paul G Allen Sch Global Hlth, Pullman, WA USA

[7] Washington State Univ, Paul G Allen Sch Global Hlth, 240 SE Ott Rd, Pullman, WA 99164 USA

[8] Univ Oslo, Inst Hlth & Soc, Fac Med, Dept Community Med & Global Hlth, Kirkeveien 166,Frederik Holsts hus, N-0450 Oslo, Norway

来源：

SCIENCE OF THE TOTAL ENVIRONMENT | 2022年 / 831卷

基金：

美国国家卫生研究院;

关键词：

Antimicrobial resistance; Geographical information system (GIS); Spatial mapping; Aquatic environment; ESBL E; coli; Water contamination; ANTIBIOTIC-RESISTANCE; FECAL CONTAMINATION; ESCHERICHIA-COLI; BETA-LACTAMASE; SURFACE-WATER; DHAKA CITY; ENTEROBACTERIACEAE; GENES; COSELECTION; BACTERIA;

D O I：

10.1016/j.scitotenv.2022.154890

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The spatial distribution of clinically important antibiotic resistant bacteria (ARB) and associated genes is important to identify the environmental distribution of contamination and 'hotspots' of antimicrobial resistance (AMR). We conducted an integrated survey of AMR in drinking water, wastewater and surface water (rivers and ponds) in three settings in Bangladesh: rural households, rural poultry farms, and urban food markets. Spatial mapping was conducted via geographic information system (GIS) using ArcGIS software. Samples (n = 397) were analyzed for the presence of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-Ec), carbapenem-resistant E. coli (CR-Ec) and resistance genes (blaCTX-M-1, blaNDM-1). In rural households, 5% of drinking water supply samples tested positive for ESBLEc, and a high proportion of wastewater, pond and river water samples were positive for ESBL-Ec (90%, 76%, and 85%, respectively). In poultry farms, 10% of drinking water samples tested positive for ESBL-Ec compared to a high prevalence in wastewater, pond and river water (90%, 68%, and 85%, respectively). CR-Ec prevalence in household wastewater and pond water was relatively low (8% and 5%, respectively) compared to river water (33%). In urban areas, 38% of drinking water samples and 98% of wastewater samples from food markets tested positive for ESBLEc while 30% of wastewater samples tested positive for CR-Ec. Wastewaters had the highest concentrations of ESBL

引用

页数：12

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