Indium-mediated Barbier-type allylation reaction in PEG400 and PEG400/H2O

被引：5

作者：

Du, Zhengyin ^{[1
]}

Wang, Fen

Zhou, Wanwei

Wang, Jin-Xian

机构：

[1] NW Normal Univ, Key Lab Ecoenvironm Related Polymer Mat, Minist Educ, Key Lab Polymer Mat Gansu Prov, Lanzhou 730070, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2010年 / 08期

关键词：

indium; allylation; homoallyl alcohols; PEG400; aqueous reaction; green synthesis; AQUEOUS-MEDIA; CARBONYL-COMPOUNDS; ORGANOMETALLIC REACTIONS; ORGANIC-SYNTHESIS; ALDEHYDES; IMINES; SYSTEM; WATER;

D O I：

10.3184/030823410X12813608471242

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A green method for the allylation of aldehydes with allyl bromide mediated by indium in polyethylene glycol 400 (PEG400) and PEG400/H2O is described. Aldehydes with different substituents afforded the corresponding homoallylic alcohols in good to excellent yields. Comparative studies show that water promoted this reaction in PEG 400.

引用

页码：475 / 477

页数：3