Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae

被引：108

作者：

Depardieu, F ^{[1
]}

Courvalin, P ^{[1
]}

机构：

[1] Inst Pasteur, Unite Agents Antibacteriens, F-75724 Paris 15, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 01期

关键词：

D O I：

10.1128/AAC.45.1.319-323.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Streptococcus pneumoniae clinical isolate BM4455 was resistant to 16-membered macrolides and to streptogramins. This unusual resistance phenotype was due to an A(2062)C (Escherichia coli numbering) mutation in domain V of the four copies of 23S rRNA.

引用

页码：319 / 323

页数：5

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