FARNESOID-X RECEPTOR AGONISTS: A NEW CLASS OF DRUGS FOR THE TREATMENT OF PBC? AN INTERNATIONAL STUDY EVALUATING THE ADDITION OF OBETICHOLIC ACID (INT-747) TO URSODEOXYCHOLIC ACID

被引：0

作者：

Mason, Andrew L. ^{[1
]}

Luketic, Velimir A. ^{[2
]}

Lindor, Keith D. ^{[3
]}

Hirschfield, Gideon M. ^{[4
]}

Gordon, Stuart C. ^{[5
]}

Mayo, Marlyn J. ^{[6
]}

Kowdley, Kris V. ^{[7
]}

Pares, Albert ^{[8
]}

Trauner, Michael ^{[9
]}

Sciacca, Cathi I. ^{[11
]}

Jones, Tessa Beecher ^{[11
]}

Pruzanski, Mark ^{[10
]}

Shapiro, David A. ^{[11
]}

机构：

[1] Univ Alberta, Edmonton, AB, Canada

[2] Virginia Commonwealth Univ, Richmond, VA USA

[3] Mayo Clin, Rochester, MN USA

[4] Univ Toronto, Toronto, ON, Canada

[5] Henry Ford Hlth Syst, Detroit, MI USA

[6] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA

[7] Virginia Mason Med Ctr, Seattle, WA 98101 USA

[8] Hosp Clin Barcelona, Digest Dis Inst, Barcelona, Spain

[9] Med Univ Graz, Graz, Austria

[10] Intercept Pharmaceut, New York, NY USA

[11] Intercept Pharmaceut, San Diego, CA USA

来源：

HEPATOLOGY | 2010年 / 52卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：357A / 357A

页数：1

共 8 条

[1] FARNESOID-X RECEPTOR AGONISTS: A NEW CLASS OF FOR THE TREATMENT OF PBC? AN INTERNATIONAL STUDY EVALUATING THE ADDITION OF INT-747 TO URSODEOXYCHOLIC ACID
Mason, A.
Luketic, V.
Lindor, K.
Hirschfield, G.
Gordon, S.
Mayo, M.
Kowdley, K.
Pares, A.
Trauner, M.
Castelloe, E.
Sciacca, C.
Jones, T. B.
Boehm, O.
Shapiro, D.
JOURNAL OF HEPATOLOGY, 2010, 52 : S1 - S2
[2] AN INTERNATIONAL STUDY EVALUATING THE FARNESOID X RECEPTOR AGONIST OBETICHOLIC ACID AS MONOTHERAPY IN PBC
Kowdley, K. V.
Jones, D.
Luketic, V.
Chapman, R.
Burroughs, A.
Hirschfield, G.
Poupon, R.
Schramm, C.
Vincent, C.
Rust, C.
Pares, A.
Mason, A.
Sciacca, C.
Beecher-Jones, T.
Bohm, O.
Castelloe, E.
Pruzanski, M.
Shapiro, D.
JOURNAL OF HEPATOLOGY, 2011, 54 : S13 - S13
[3] THE FIRST NEW MONOTHERAPY THERAPEUTIC PBC STUDY IN A DECADE? AN INTERNATIONAL STUDY EVALUATING THE FARNESOID X RECEPTOR AGONIST OBETICHOLIC ACID IN PBC
Jones, D.
Kowdley, K.
Chapman, R.
Burroughs, A.
Hirschfield, G.
Schramm, C.
Poupon, R.
ParEs, A.
Shapiro, D.
Pruzanski, M.
GUT, 2011, 60 : A50 - A50
[4] THE FIRST NEW MONOTHERAPY THERAPEUTIC PBC STUDY IN A DECADE? AN INTERNATIONAL STUDY EVALUATING THE FARNESOID X RECEPTOR AGONIST OBETICHOLIC ACID IN PBC
Kowdley, Kris V.
Luketic, Velimir A.
Jones, David E.
Chapman, Roger W.
Burroughs, Andrew K.
Hirschfield, Gideon M.
Poupon, Raoul
Schramm, Christoph
Vincent, Catherine
Rust, Christian
Pares, Albert
Mason, Andrew L.
Castelloe, Erin N.
Sciacca, Cathi I.
Boehm, Olaf
Pruzanski, Mark
Shapiro, David A.
HEPATOLOGY, 2011, 54 : 416A - 417A
[5] THE FARNESOID X RECEPTOR (FXR) AGONIST OBETICHOLIC ACID (INT-747, 6α-ETHYL CHENODEOXYCHOLIC ACID) IN COMBINATION WITH URSODEOXYCHOLIC ACID (UDCA) INCREASES PLASMA FGF-19 CONCENTRATIONS BUT NOT BILE ACID CONCENTRATION OR PROFILE IN PRIMARY BILIARY CIRRHOSIS (PBC)
Marschall, Hanns-Ulrich
Luketic, Velimir A.
Mason, Andrew L.
Lindor, Keith D.
Hirschfield, Gideon M.
Gordon, Stuart C.
Mayo, Marlyn J.
Kowdley, Kris V.
Pares, Albert
Trauner, Michael
Eliot, Lise
Hofmann, Alan F.
Sciacca, Cathi I.
Shapiro, David A.
HEPATOLOGY, 2010, 52 (04) : 355A - 356A
[6] The First New Trials for Primary Biliary Cirrhosis in a Decade: An International Program Evaluating the Farnesoid X Receptor Agonist Obeticholic Acid
Kowdley, Kris y
Nevens, Frederik
Andreone, Pietro
Luketic, Velimir A.
Shah, Hemant
Pencek, Richard
Marmon, Tonya K.
Shapiro, David
GASTROENTEROLOGY, 2015, 148 (04) : S991 - S992
[7] Farnesoid X Receptor Obeticholic Acid Improves both Liver Complications and Atherosclerosis in the Obese, Insulin Resistant, Diet-Induced NASH (DIN) Mouse. A Nutritional Model for Evaluating Drugs Affecting Non-Alcoholic Liver Diseases.
Briand, Francois
Brousseau, Emmanuel
Quinsat, Marjolaine
Costard, Clement
Sulpice, Thierry
HEPATOLOGY, 2016, 64 : 72A - 72A
[8] Farnesoid X Receptor Agonist Obeticholic Acid Raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-induced NASH (DIN) Hamster, a Novel Preclinical Model for Evaluating Efficacy and Side effects of Drugs targeting Non-Alcoholic Liver Diseases
Briand, Francois
Brocas, Solene
Quinsat, Marjolaine
Brousseau, Emmanuel
Sulpice, Thierry
HEPATOLOGY, 2016, 64 (06) : 1135A - 1136A

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