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A systematic look at an old problem
被引:219
作者
:
Kirkwood, Thomas B. L.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle, Integrated Syst Biol Ageing & Nutr, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Univ Newcastle, Integrated Syst Biol Ageing & Nutr, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Kirkwood, Thomas B. L.
[
1
]
机构
:
[1]
Univ Newcastle, Integrated Syst Biol Ageing & Nutr, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
来源
:
NATURE
|
2008年
/ 451卷
/ 7179期
基金
:
英国生物技术与生命科学研究理事会;
关键词
:
D O I
:
10.1038/451644a
中图分类号
:
O [数理科学和化学];
P [天文学、地球科学];
Q [生物科学];
N [自然科学总论];
学科分类号
:
07 ;
0710 ;
09 ;
摘要
:
[No abstract available]
引用
收藏
页码:644 / 647
页数:4
相关论文
共 30 条
[1]
High oxidative damage levels in the longest-living rodent, the naked mole-rat
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0
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0
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CUNY City Coll, Dept Biol, New York, NY 10031 USA
Andziak, Blazej
O'Connor, Timothy P.
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h-index:
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CUNY City Coll, Dept Biol, New York, NY 10031 USA
O'Connor, Timothy P.
Qi, Wenbo
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0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Qi, Wenbo
DeWaal, Eric M.
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0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
DeWaal, Eric M.
Pierce, Anson
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0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Pierce, Anson
Chaudhuri, Asish R.
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Chaudhuri, Asish R.
Van Remmen, Holly
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Van Remmen, Holly
Buffenstein, Rochelle
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Buffenstein, Rochelle
[J].
AGING CELL,
2006,
5
(06):
: 463
-
471
[2]
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
Bender, A
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Bender, A
Krishnan, KJ
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Krishnan, KJ
Morris, CM
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Morris, CM
Taylor, GA
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Taylor, GA
Reeve, AK
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Reeve, AK
Perry, RH
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0
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h-index:
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Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
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Jaros, E
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0
引用数:
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h-index:
0
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Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
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Hersheson, JS
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0
h-index:
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Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
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Betts, J
论文数:
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0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Betts, J
Klopstock, T
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Klopstock, T
Taylor, RW
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h-index:
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Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
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Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
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Turnbull, DM
[J].
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[3]
Cellular senescence: when bad things happen to good cells
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论文数:
0
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Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA
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di Fagagna, Fabrizio d'Adda
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA
di Fagagna, Fabrizio d'Adda
[J].
NATURE REVIEWS MOLECULAR CELL BIOLOGY,
2007,
8
(09)
: 729
-
740
[4]
Esiri MM, 2001, LANCET, V357, P169
[5]
Finch C., 2000, CHANCE DEV AGING
[6]
Stochastic and genetic factors influence tissue-specific decline in ageing C-elegans
Herndon, LA
论文数:
0
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0
h-index:
0
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Herndon, LA
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h-index:
0
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Dudaronek, JM
Brown, PA
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Listner, KM
Sakano, Y
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h-index:
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Sakano, Y
Paupard, MC
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h-index:
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引用数:
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h-index:
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Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
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[J].
NATURE,
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(6909)
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[7]
Positive correlation between mammalian life span and cellular resistance to stress
Kapahi, P
论文数:
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引用数:
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h-index:
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Kapahi, P
Boulton, ME
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Manchester, Dept Geriatr Med, Biol Gerontol Grp, Manchester M13 9PT, Lancs, England
Boulton, ME
Kirkwood, TBL
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Manchester, Dept Geriatr Med, Biol Gerontol Grp, Manchester M13 9PT, Lancs, England
Kirkwood, TBL
[J].
FREE RADICAL BIOLOGY AND MEDICINE,
1999,
26
(5-6)
: 495
-
500
[8]
Towards an e-biology of ageing: integrating theory and data
Kirkwood, TBL
论文数:
0
引用数:
0
h-index:
0
机构:
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Kirkwood, TBL
Boys, RJ
论文数:
0
引用数:
0
h-index:
0
机构:
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Boys, RJ
Gillespie, CS
论文数:
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h-index:
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Shanley, DP
论文数:
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引用数:
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h-index:
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Wilkinson, DJ
论文数:
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0
h-index:
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[J].
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Newcastle Univ, Inst Ageing & Hlth, Henry Wellcome Lab Biogerontol Res, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
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[J].
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Kirkwood, TBL
Finch, CE
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Finch, CE
[J].
NATURE,
2002,
419
(6909)
: 794
-
795
←
1
2
3
→
共 30 条
[1]
High oxidative damage levels in the longest-living rodent, the naked mole-rat
Andziak, Blazej
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Andziak, Blazej
O'Connor, Timothy P.
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
O'Connor, Timothy P.
Qi, Wenbo
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Qi, Wenbo
DeWaal, Eric M.
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
DeWaal, Eric M.
Pierce, Anson
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Pierce, Anson
Chaudhuri, Asish R.
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Chaudhuri, Asish R.
Van Remmen, Holly
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Van Remmen, Holly
Buffenstein, Rochelle
论文数:
0
引用数:
0
h-index:
0
机构:
CUNY City Coll, Dept Biol, New York, NY 10031 USA
CUNY City Coll, Dept Biol, New York, NY 10031 USA
Buffenstein, Rochelle
[J].
AGING CELL,
2006,
5
(06):
: 463
-
471
[2]
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
Bender, A
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Bender, A
Krishnan, KJ
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Krishnan, KJ
Morris, CM
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Morris, CM
Taylor, GA
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Taylor, GA
Reeve, AK
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Reeve, AK
Perry, RH
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Perry, RH
Jaros, E
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Jaros, E
Hersheson, JS
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Hersheson, JS
Betts, J
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Betts, J
Klopstock, T
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Klopstock, T
Taylor, RW
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Taylor, RW
Turnbull, DM
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Univ Newcastle Upon Tyne, Sch Med, Mitochondrial Res Grp, Sch Neurol Neurobiol & Psychiat, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
Turnbull, DM
[J].
NATURE GENETICS,
2006,
38
(05)
: 515
-
517
[3]
Cellular senescence: when bad things happen to good cells
Campisi, Judith
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA
Campisi, Judith
di Fagagna, Fabrizio d'Adda
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA
di Fagagna, Fabrizio d'Adda
[J].
NATURE REVIEWS MOLECULAR CELL BIOLOGY,
2007,
8
(09)
: 729
-
740
[4]
Esiri MM, 2001, LANCET, V357, P169
[5]
Finch C., 2000, CHANCE DEV AGING
[6]
Stochastic and genetic factors influence tissue-specific decline in ageing C-elegans
Herndon, LA
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Herndon, LA
Schmeissner, PJ
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Schmeissner, PJ
Dudaronek, JM
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Dudaronek, JM
Brown, PA
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Brown, PA
Listner, KM
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Listner, KM
Sakano, Y
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Sakano, Y
Paupard, MC
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Paupard, MC
Hall, DH
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Hall, DH
Driscoll, M
论文数:
0
引用数:
0
h-index:
0
机构:
Rutgers State Univ, Dept Mol Biol & Biochem, Nelson Biol Labs A232, Piscataway, NJ 08854 USA
Driscoll, M
[J].
NATURE,
2002,
419
(6909)
: 808
-
814
[7]
Positive correlation between mammalian life span and cellular resistance to stress
Kapahi, P
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Manchester, Dept Geriatr Med, Biol Gerontol Grp, Manchester M13 9PT, Lancs, England
Kapahi, P
Boulton, ME
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Manchester, Dept Geriatr Med, Biol Gerontol Grp, Manchester M13 9PT, Lancs, England
Boulton, ME
Kirkwood, TBL
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Manchester, Dept Geriatr Med, Biol Gerontol Grp, Manchester M13 9PT, Lancs, England
Kirkwood, TBL
[J].
FREE RADICAL BIOLOGY AND MEDICINE,
1999,
26
(5-6)
: 495
-
500
[8]
Towards an e-biology of ageing: integrating theory and data
Kirkwood, TBL
论文数:
0
引用数:
0
h-index:
0
机构:
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Kirkwood, TBL
Boys, RJ
论文数:
0
引用数:
0
h-index:
0
机构:
Newcastle Univ, Newcastle Gen Hosp, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
Boys, RJ
Gillespie, CS
论文数:
0
引用数:
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