Preparation of porphyrin and phthalocyanine conjugates for biomedical applications

被引:4
|
作者
Ponton, Iris [1 ]
Sanchez-Garcia, David [1 ]
机构
[1] Univ Ramon Llull, Inst Quim Sarria, Grp Engn Mat GEMAT, Via Augusta 390, Barcelona 08017, Spain
关键词
porphyrin; phthalocyanine; PDT; cleavable-linker; conjugation; AMIDE BOND FORMATION; CLICK CHEMISTRY; PHOTODYNAMIC THERAPY; DRUG-DELIVERY; ACTIVATABLE PHOTOSENSITIZER; ZINC PHTHALOCYANINE; CHEMICAL-SYNTHESIS; IN-VITRO; PRODRUG; ISOTHIOCYANATES;
D O I
10.1142/S1088424621300068
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The aim of this review is to offer a succinct overview of the main synthetic techniques used in the preparation of conjugates containing porphyrins, including chlorins and bacteriochlorins and phthalocyanines for biomedical applications and photodynamic therapy (PDT). To illustrate the conjugation techniques representative examples from the literature will be presented. The aim of this review is to offer a succinct overview of the main synthetic techniques used in the preparation of conjugates containing porphyrins, including chlorins and bacteriochlorins and phthalocyanines for biomedical applications and photodynamic therapy (PDT). To illustrate the conjugation techniques, representative examples from the literature are presented.
引用
收藏
页码:917 / 929
页数:13
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