A highly sensitive. and selective off-on fluorescent chemosensor for hydrazine based on coumarin β-diketone

被引：43

作者：

Wu, Wei-Na ^{[1
]}

Wu, Hao ^{[1
]}

Wang, Yuan ^{[1
]}

Mao, Xian-Jie ^{[1
]}

Zhao, Xiao-Lei ^{[1
]}

Xu, Zhou-Qing ^{[1
]}

Fan, Yun-Chang ^{[1
]}

Xu, Zhi-Hong ^{[2
]}

机构：

[1] Henan Polytech Univ, Coll Chem & Chem Engn, Jiaozuo 454000, Peoples R China

[2] Xuchang Univ, Sch Chem & Chem Engn, Key Lab Chemo Biosensing & Detect, Xuchang 461000, Henan, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2018年 / 188卷

基金：

中国国家自然科学基金;

关键词：

Fluorescent probe; Coumarin; Hydrazine; beta-Diketone; Cell imaging; AQUEOUS-SOLUTION; IN-VIVO; GAS STATE; CHEMODOSIMETRIC PROBE; RATIOMETRIC DETECTION; RAPID DETECTION; SENSOR; ESIPT;

D O I：

10.1016/j.saa.2017.06.062

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

A coumarin-based sensor C1, namely 3-acetoacetylcoumarin was designed, synthesized and applied for hydrazine detection. Hydrazinolysis of the chemosensor gives a fluorescent coumarin-pyrazole product C1 - N2H4 [3-(3-methyl-1H-pyrazol-5-yl)coumarin], and thus resulting in a prominent fluorescence off-on response toward hydrazine under physiological conditions. The probe is highly selective toward hydrazine over cations, anions and other biologically/environmentally abundant analytes. The detection limit of the probe is 3.2 ppb. The sensing mechanism was supported by H-1 NMR, IR, MS and OFT calculation. The application of the fluorescent probe in monitoring intracellular hydrazine in glioma cell line U251 was also demonstrated. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：80 / 84

页数：5

共 38 条

[1]

[Anonymous], 1996, SADABS

[2] Hydrazine-Selective Chromogenic and Fluorogenic Probe Based on Levulinated Coumarin [J].

Choi, Myung Gil ;

Hwang, Jiyoung ;

Moon, Jung Ok ;

Sung, Jaeyoung ;

Chang, Suk-Kyu .

ORGANIC LETTERS, 2011, 13 (19) :5260-5263

[3] Unique Tr-Output Optical Probe for Specific and Ultrasensitive Detection of Hydrazine [J].

Cui, Lei ;

Ji, Chunfei ;

Peng, Zhixing ;

Zhong, Lin ;

Zhou, Chaohui ;

Yan, Luliang ;

Qu, Song ;

Zhang, Shuping ;

Huang, Chusen ;

Qian, Xuhong ;

Xu, Yufang .

ANALYTICAL CHEMISTRY, 2014, 86 (09) :4611-4617

[4] Hydrazine detection in the gas state and aqueous solution based on the Gabriel mechanism and its imaging in living cells [J].

Cui, Lei ;

Peng, Zhixing ;

Ji, Chunfei ;

Huang, Junhai ;

Huang, Dongting ;

Ma, Jie ;

Zhang, Shuping ;

Qian, Xuhong ;

Xu, Yufang .

CHEMICAL COMMUNICATIONS, 2014, 50 (12) :1485-1487

[5] A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging [J].

Dai, Xi ;

Wang, Zhao-Yang ;

Du, Zhi-Fang ;

Miao, Jun-Ying ;

Zhao, Bao-Xiang .

SENSORS AND ACTUATORS B-CHEMICAL, 2016, 232 :369-374

[6] A quick response fluorescent probe based on coumarin and quinone for glutathione and its application in living cells [J].

Dai, Xi ;

Du, Zhi-Fang ;

Wang, Li-Hong ;

Miao, Jun-Ying ;

Zhao, Bao-Xiang .

ANALYTICA CHIMICA ACTA, 2016, 922 :64-70

[7] An ICT-based ratiometric probe for hydrazine and its application in live cells [J].

Fan, Jiangli ;

Sun, Wen ;

Hu, Mingming ;

Cao, Jianfang ;

Cheng, Guanghui ;

Dong, Huijuan ;

Song, Kedong ;

Liu, Yingchao ;

Sun, Shiguo ;

Peng, Xiaojun .

CHEMICAL COMMUNICATIONS, 2012, 48 (65) :8117-8119

[8]

Frisch, 2016, GAUSSIAN 16 REVISION

[9] Fast and ratiometric "naked eye'' detection of hydrazine for both solid and vapour phase sensing [J].

Goswami, Shyamaprosad ;

Paul, Sima ;

Manna, Abhishek .

NEW JOURNAL OF CHEMISTRY, 2015, 39 (03) :2300-2305

[10] Rapid detection of hydrazine in a naphthol-fused chromenyl loop and its effectiveness in human lung cancer cells: tuning remarkable selectivity via the reaction altered pathway supported by theoretical studies [J].

Goswami, Shyamaprosad ;

Das, Avijit Kumar ;

Saha, Urmila ;

Maity, Sibaprasad ;

Khanra, Kalyani ;

Bhattacharyya, Nandan .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 13 (07) :2134-2139

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