Benefits and Risks of Moderate Alcohol Consumption on Cardiovascular Disease: Current Findings and Controversies

被引：117
作者：
Chiva-Blanch, Gemma [1 ,2 ]
Badimon, Lina [1 ,2 ,3 ]
机构：
[1] Cardiovasc Program ICCC, St Antoni Maria Claret 167, Barcelona 08025, Spain
[2] Hosp Santa Creu & St Pau IIB St Pau, Inst Recerca, St Antoni Maria Claret 167, Barcelona 08025, Spain
[3] Inst Salud Carlos III ISCIII, CIBER Enfermedades Cardiovasc CIBERCV, Madrid 28029, Spain
来源：
NUTRIENTS | 2020年 / 12卷 / 01期
关键词：
alcohol; cardiovascular disease; polyphenols; wine; beer; spirits; myocardial infarction; stroke; hypertension; cholesterol; CORONARY-HEART-DISEASE; DOSE-RESPONSE METAANALYSIS; ALL-CAUSE MORTALITY; INCIDENT ATRIAL-FIBRILLATION; MYOCARDIAL-INFARCTION; ATHEROSCLEROSIS RISK; GENDER-DIFFERENCES; RED WINE; REDUCED MORTALITY; HEAVY DRINKING;
D O I：
10.3390/nu12010108
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Alcohol has a hormetic physiological behavior that results in either increased or decreased cardiovascular risk depending on the amount consumed, drinking frequency, pattern of consumption, and the outcomes under study or even the type of alcoholic beverage consumed. However, the vast majority of studies elucidating the role of alcohol in cardiovascular and in the global burden of disease relies on epidemiological studies of associative nature which carry several limitations. This is why the cardiovascular benefits of low-moderate alcohol consumption are being questioned and perhaps might have been overestimated. Thus, the aim of this review was to critically discuss the current knowledge on the relationship between alcohol intake and cardiovascular disease. Besides new evidence associating low and moderate alcohol consumption with decreased risk of cardiovascular disease, several questions remain unanswered related to the concrete amount of safe consumption, the type of alcoholic beverage, and the age-, sex-, and genetic/ethnical-specific differences in alcohol consumption.
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页数：19
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