Stability of small mesoporous silica nanoparticles in biological media

被引：141
|
作者：
Lin, Yu-Shen [1 ]
Abadeer, Nardine [1 ]
Haynes, Christy L. [1 ]
机构：
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 01期
关键词：
SIZE; FUNCTIONALIZATION; SYSTEM;
D O I：
10.1039/c0cc02923h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this work, sub-50 nm pegylated mesoporous silica nanoparticles prepared with hydrothermal treatment are shown to have long-term stability in various media at both room and physiological temperature. Compared to bare mesoporous silica nanoparticles, the highly pegylated mesoporous silica nanoparticles show significantly improved biocompatibility and decreased macrophage uptake, making these nanoparticles viable for in vivo stealth drug delivery applications.
引用
收藏
页码：532 / 534
页数：3
相关论文
共 50 条
  • [41] Colloidal stability and degradability of silica nanoparticles in biological fluids: a review
    da Cruz Schneid, Andressa
    Albuquerque, Lindomar Jose Calumby
    Mondo, Gabriela Borba
    Ceolin, Marcelo
    Picco, Agustin Silvio
    Cardoso, Mateus Borba
    JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2022, 102 (01) : 41 - 62
  • [42] Colloidal stability and degradability of silica nanoparticles in biological fluids: a review
    Andressa da Cruz Schneid
    Lindomar Jose Calumby Albuquerque
    Gabriela Borba Mondo
    Marcelo Ceolin
    Agustin Silvio Picco
    Mateus Borba Cardoso
    Journal of Sol-Gel Science and Technology, 2022, 102 : 41 - 62
  • [43] Mesoporous silica nanoparticles and osteoporosis
    Manzano, M.
    Lozano, D.
    Vallet-Regi, M.
    REVISTA DE OSTEOPOROSIS Y METABOLISMO MINERAL, 2022, 14 (04) : 101 - 103
  • [44] Dissolution control and stability improvement of silica nanoparticles in aqueous media
    Laura Spitzmüller
    Fabian Nitschke
    Bastian Rudolph
    Jonathan Berson
    Thomas Schimmel
    Thomas Kohl
    Journal of Nanoparticle Research, 2023, 25
  • [45] Dissolution control and stability improvement of silica nanoparticles in aqueous media
    Spitzmueller, Laura
    Nitschke, Fabian
    Rudolph, Bastian
    Berson, Jonathan
    Schimmel, Thomas
    Kohl, Thomas
    JOURNAL OF NANOPARTICLE RESEARCH, 2023, 25 (03)
  • [46] Biomedical application of mesoporous silica nanoparticles as delivery systems: a biological safety perspective
    Hosseinpour, Sepanta
    Walsh, Laurence J.
    Xu, Chun
    JOURNAL OF MATERIALS CHEMISTRY B, 2020, 8 (43) : 9863 - 9876
  • [47] Investigation of the stability of Platinum nanoparticles incorporated in mesoporous silica with different pore sizes
    Yano, Kazuhisa
    Zhang, Shuyi
    Pan, Xiaoqing
    Tatsuda, Narihito
    JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2014, 421 : 22 - 26
  • [48] Enhanced Activity and Stability of Lysozyme by Immobilization in the Matching Nanochannels of Mesoporous Silica Nanoparticles
    Kao, Kun-Che
    Lin, Tien-Sung
    Mou, Chung-Yuan
    JOURNAL OF PHYSICAL CHEMISTRY C, 2014, 118 (13): : 6734 - 6743
  • [49] Insight into mesoporous silica nanoparticles for embedding and improving environmental and digestive stability of cannabidiol
    Yu, Rui
    Xu, Heyang
    Gantumur, Munkh-Amgalan
    Bilawal, Akhunzada
    Jiang, Zhanmei
    Pan, Mingzhe
    FOOD BIOSCIENCE, 2024, 62
  • [50] Small sized mesoporous silica nanoparticles functionalized with mannose for retinoblastoma cell imaging
    Warther, David
    Jimenez, Chiara Mauriello
    Raehm, Laurence
    Gerardin, Corine
    Durand, Jean-Olivier
    Morere, Alain
    El Cheikh, Khaled
    Gallud, Audrey
    Gary-Bobo, Magali
    Maynadier, Marie
    Garcia, Marcel
    RSC ADVANCES, 2014, 4 (70): : 37171 - 37179
12345