Dibenzothiophene Sulfoximine as an NH3 Surrogate in the Synthesis of Primary Amines by Copper-Catalyzed C-X and C-H Bond Amination

被引：60
|
作者：
Li, Zhen [1 ]
Yu, Hao [1 ]
Bolm, Carsten [1 ]
机构：
[1] Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2017年 / 56卷 / 32期
关键词：
amination; dibenzothiophene sulfoximine; NH3; surrogates; primary amines; radical cleavage; N-ARYLATIONS; PALLADIUM; AMIDATION; AZIDES; PHOTOCHEMISTRY; COMPATIBILITY; GENERATION; ANILINES; NITRENE; AMMONIA;
D O I：
10.1002/anie.201705025
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Readily accessible dibenzothiophene sulfoximine is an NH3 surrogate allowing the preparation of free anilines by copper-catalyzed cross-coupling reactions with aryl iodides or amides followed by radical S-N bond cleavage. The one-pot/two-step reactions sequence leads to the aminated products in good yields.
引用
收藏
页码：9532 / 9535
页数：4
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