Protein import and export across the bacterial outer membrane

被引：5

作者：

Guerin, Jeremy ^{[1
]}

Buchanan, Susan K. ^{[1
]}

机构：

[1] NIDDK, Lab Mol Biol, NIH, Bethesda, MD 20892 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2021年 / 69卷

关键词：

2-PARTNER SECRETION; FILAMENTOUS HEMAGGLUTININ; MOLECULAR-BASIS; DOMAIN; TRANSPORTER; SYSTEMS; SUGGESTS; REVEALS; GROWTH;

D O I：

10.1016/j.sbi.2021.03.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The bacterial outer membrane forms an impermeable barrier to the environment, but a wide variety of substances must cross it without compromising the membrane. Perhaps, the most fascinating transport phenomenon is the import and export of very large protein toxins using relatively small beta-barrel proteins residing in the outer membrane. Progress has been made on three systems in recent years that shed light on this process. In this review, we summarize bacteriocin (toxin) import using TonB-dependent transporters and protein secretion by autotransporters and two partner secretion systems.

引用

收藏

页码：55 / 62

页数：8

相关论文

共 53 条

[1] A comparative genomics approach identifies contact-dependent growth inhibition as a virulence determinant [J].

Allen, Jonathan P. ;

Ozer, Egon A. ;

Minasov, George ;

Shuvalova, Ludmilla ;

Kiryukhina, Olga ;

Satchell, Karla J. F. ;

Hauser, Alan R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (12) :6811-6821

[2] Sequential Unfolding of Beta Helical Protein by Single-Molecule Atomic Force Microscopy [J].

Alsteens, David ;

Martinez, Nicolas ;

Jamin, Marc ;

Jacob-Dubuisson, Francois .

PLOS ONE, 2013, 8 (08)

[3] Contact-dependent inhibition of growth in Escherichia coli [J].

Aoki, SK ;

Pamma, R ;

Hernday, AD ;

Bickham, JE ;

Braaten, BA ;

Low, DA .

SCIENCE, 2005, 309 (5738) :1245-1248

[4] A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria [J].

Aoki, Stephanie K. ;

Diner, Elie J. ;

de Roodenbeke, Claire t'Kint ;

Burgess, Brandt R. ;

Poole, Stephen J. ;

Braaten, Bruce A. ;

Jones, Allison M. ;

Webb, Julia S. ;

Hayes, Christopher S. ;

Cotter, Peggy A. ;

Low, David A. .

NATURE, 2010, 468 (7322) :439-442

[5] Autotransporter structure reveals intra-barrel cleavage followed by conformational changes [J].

Barnard, Travis J. ;

Dautin, Nathalie ;

Lukacik, Petra ;

Bernstein, Harris D. ;

Buchanan, Susan K. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (12) :1214-1220

[6] Translocation path of a substrate protein through its Omp85 transporter [J].

Baud, Catherine ;

Guerin, Jeremy ;

Petit, Emmanuelle ;

Lesne, Elodie ;

Dupre, Elian ;

Locht, Camille ;

Jacob-Dubuisson, Francoise .

NATURE COMMUNICATIONS, 2014, 5

[7] Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport [J].

Behrens, Hannah M. ;

Lowe, Edward D. ;

Gault, Joseph ;

Housden, Nicholas G. ;

Kaminska, Renata ;

Weber, T. Moritz ;

Thompson, Catriona M. A. ;

Mislin, Gaetan L. A. ;

Schalk, Isabelle J. ;

Walker, Daniel ;

Robinson, Carol, V ;

Kleanthous, Colin .

MBIO, 2020, 11 (02)

[8] Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import [J].

Buchanan, Susan K. ;

Lukacik, Petra ;

Grizot, Sylvestre ;

Ghirlando, Rodolfo ;

Ali, Maruf M. U. ;

Barnard, Travis J. ;

Jakes, Karen S. ;

Kienker, Paul K. ;

Esser, Lothar .

EMBO JOURNAL, 2007, 26 (10) :2594-2604

[9] Antibacterial Weapons: Targeted Destruction in the Microbiota [J].

Chassaing, Benoit ;

Cascales, Eric .

TRENDS IN MICROBIOLOGY, 2018, 26 (04) :329-338

[10] Insights into the autotransport process of a trimeric autotransporter, Yersinia Adhesin A (YadA) [J].

Chauhan, Nandini ;

Hatlem, Daniel ;

Orwick-Rydmark, Marcella ;

Schneider, Kenneth ;

Floetenmeyer, Matthias ;

van Rossum, Barth ;

Leo, Jack C. ;

Linke, Dirk .

MOLECULAR MICROBIOLOGY, 2019, 111 (03) :844-862

← 1 2 3 4 5 6 →