Doxorubicin pathways: pharmacodynamics and adverse effects

被引：1295

作者：

Thorn, Caroline F. ^{[1
]}

Oshiro, Connie ^{[1
]}

Marsh, Sharon ^{[5
]}

Hernandez-Boussard, Tina ^{[2
]}

McLeod, Howard ^{[4
]}

Klein, Teri E. ^{[1
]}

Altman, Russ B. ^{[1
,3
]}

机构：

[1] Stanford Univ, Med Ctr, Dept Genet, Stanford, CA 94305 USA

[2] Stanford Univ, Med Ctr, Dept Surg, Stanford, CA 94305 USA

[3] Stanford Univ, Med Ctr, Dept Bioengn, Stanford, CA 94305 USA

[4] Univ N Carolina, Inst Pharmacogenom & Individualized Therapy, Chapel Hill, NC USA

[5] Univ Alberta, Fac Pharm & Pharmaceut Sci, Edmonton, AB T6G 2N8, Canada

来源：

PHARMACOGENETICS AND GENOMICS | 2011年 / 21卷 / 07期

关键词：

ABCC1; ABCC2; anthracyclines; cardiotoxicity; CAT; CBR3; CYBA; doxorubicin; drug resistance; NCF4; pharmacogenomics; PharmGKBpathways; RAC2; CONGESTIVE-HEART-FAILURE; BREAST-CANCER PATIENTS; MULTIDRUG-RESISTANCE; LUNG-CANCER; IN-VITRO; ANTHRACYCLINE CARDIOTOXICITY; GENETIC POLYMORPHISMS; TOPOISOMERASE-II; NITRIC-OXIDE; PHARMACOGENETICS;

D O I：

10.1097/FPC.0b013e32833ffb56

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：440 / 446

页数：7

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