The Efficacy of Lenvatinib and Everolimus in Chromophobe-type Non-Clear-Cell Renal Cell Carcinoma: A Case Report and Literature Review

被引：3
|
作者：
Schwartz, Candice [1 ]
Pfanzelter, Nicklas [2 ]
Kuzel, Timothy M. [2 ]
机构：
[1] Rush Univ, Med Ctr, Dept Internal Med, Chicago, IL 60612 USA
[2] Rush Univ, Med Ctr, Dept Internal Med, Div Hematol Oncol Cell Therapy, Chicago, IL 60612 USA
来源：
CLINICAL GENITOURINARY CANCER | 2017年 / 15卷 / 05期
关键词：
Chromophobe; Everolimus; Lenvatinib; Noneclear-cell renal cell carcinoma; Treatment; OPEN-LABEL; SUNITINIB; MULTICENTER; PHASE-2;
D O I：
10.1016/j.clgc.2017.05.017
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
First- and second-line treatments for metastatic none clear-cell renal cell carcinoma (nccRCC) are not extensively studied and based on the well-defined treatments for metastatic clear cell renal cell carcinoma (ccRCC). Lenvatinib and everolimus have been studied in patients with ccRCC and are now established second-line therapy. This case report describes the use of lenvatinib and everolimus in a patient with metastatic nccRCC, and resultant marked reduction in tumor burden. Although it has been studied in patients with ccRCC, additional trials evaluating lenvatinib and everolimus may confirm the efficacy of this treatment regimen in patients with nccRCC.
引用
收藏
页码：E903 / E906
页数：4
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