Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment

被引：4541

作者：

Chen, Liang-Kung ^{[1
,2
]}

Woo, Jean ^{[3
]}

Assantachai, Prasert ^{[4
]}

Auyeung, Tung-Wai ^{[5
]}

Chou, Ming-Yueh ^{[1
,6
]}

Iijima, Katsuya ^{[7
]}

Jang, Hak Chul ^{[8
]}

Kang, Lin ^{[9
]}

Kim, Miji ^{[10
]}

Kim, Sunyoung ^{[11
]}

Kojima, Taro ^{[12
]}

Kuzuya, Masafumi ^{[13
]}

Lee, Jenny S. W. ^{[5
]}

Lee, Sang Yoon ^{[14
,15
]}

Lee, Wei-Ju ^{[1
,16
]}

Lee, Yunhwan ^{[17
]}

Liang, Chih-Kuang ^{[1
,6
]}

Lim, Jae-Young ^{[14
]}

Lim, Wee Shiong ^{[18
]}

Peng, Li-Ning ^{[1
,2
]}

Sugimoto, Ken ^{[19
]}

Tanaka, Tomoki ^{[6
]}

Won, Chang Won ^{[11
]}

Yamada, Minoru ^{[20
]}

Zhang, Teimei ^{[21
]}

Akishita, Masahiro ^{[12
]}

Arai, Hidenori ^{[22
]}

机构：

[1] Natl Yang Ming Univ, Aging & Hlth Res Ctr, Taipei, Taiwan

[2] Taipei Vet Gen Hosp, Ctr Geriatr & Gerontol, 201,Sec 2,Shih Pai Rd, Taipei 11217, Taiwan

[3] Chinese Univ Hong Kong, Fac Med, Dept Med & Therapeut, Hong Kong, Peoples R China

[4] Mahidol Univ, Siriraj Hosp, Dept Prevent & Social Med, Div Geriatr Med,Fac Med, Bangkok, Thailand

[5] Chinese Univ Hong Kong, SH Ho Ctr Gerontol & Geriatr, Hong Kong, Peoples R China

[6] Kaohsiung Vet Gen Hosp, Ctr Geriatr & Gerontol, Kaohsiung, Taiwan

[7] Univ Tokyo, Inst Gerontol, Tokyo, Japan

[8] Seoul Natl Univ, Coll Med, Dept Internal Med, Bundang Hosp, Seongnam, South Korea

[9] Peking Union Med Coll Hosp, Dept Geriatr, Beijing, Peoples R China

[10] Kyung Hee Univ, Coll Med, East West Med Res Inst, Dept Biomed Sci & Technol, Seoul, South Korea

[11] Kyung Hee Univ, Coll Med, Dept Family Med, Seoul, South Korea

[12] Univ Tokyo, Grad Sch Med, Dept Geriatr Med, Tokyo, Japan

[13] Nagoya Univ, Dept Community Healthcare & Geriatr, Grad Sch Med, Nagoya, Aichi, Japan

[14] Seoul Natl Univ, Coll Med, Dept Rehabil Med, Bundang Hosp, Seongnam, South Korea

[15] Seoul Natl Univ, Dept Rehabil Med, Boramae Med Ctr, Seoul, South Korea

[16] Taipei Vet Gen Hosp, Dept Family Med, Yuanshan Branch, Yilan, Taiwan

[17] Ajou Univ, Dept Prevent Med & Publ Hlth, Sch Med, Suwon, South Korea

[18] Tan Tock Seng Hosp, Inst Geriatr & Act Aging, Singapore, Singapore

[19] Osaka Univ, Dept Geriatr Med, Grad Sch Med, Osaka, Japan

[20] Univ Tsukuba, Grad Sch Comprehens Human Sci, Tokyo, Japan

[21] Minist Hlth, Beijing Inst Geriatr, Beijing Hosp, Beijing, Peoples R China

[22] Natl Ctr Geriatr & Gerontol, 7-430 Morioka Cho, Obu, Aichi 4740038, Japan

来源：

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION | 2020年 / 21卷 / 03期

关键词：

Sarcopenia; skeletal muscle strength and mass; physical performance; diagnosis; Asia; criteria; SKELETAL-MUSCLE MASS; QUALITY-OF-LIFE; DWELLING OLDER-ADULTS; SARC-F QUESTIONNAIRE; PHYSICAL-ACTIVITY; ELDERLY-PATIENTS; LONGITUDINAL ANALYSIS; BODY-COMPOSITION; GRIP STRENGTH; GAIT SPEED;

D O I：

10.1016/j.jamda.2019.12.012

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Clinical and research interest in sarcopenia has burgeoned internationally, Asia included. The Asian Working Group for Sarcopenia (AWGS) 2014 consensus defined sarcopenia as "age-related loss of muscle mass, plus low muscle strength, and/or low physical performance" and specified cutoffs for each diagnostic component; research in Asia consequently flourished, prompting this update. AWGS 2019 retains the previous definition of sarcopenia but revises the diagnostic algorithm, protocols, and some criteria: low muscle strength is defined as handgrip strength <28 kg for men and <18 kg for women; criteria for low physical performance are 6-m walk <1.0 m/s, Short Physical Performance Battery score <= 9, or 5-time chair stand test >= 12 seconds. AWGS 2019 retains the original cutoffs for height-adjusted muscle mass: dual-energy X-ray absorptiometry, <7.0 kg/m(2) in men and <5.4 kg/m(2) in women; and bioimpedance, <7.0 kg/m(2) in men and <5.7 kg/m(2) in women. In addition, the AWGS 2019 update proposes separate algorithms for community vs hospital settings, which both begin by screening either calf circumference (<34 cm in men, <33 cm in women), SARC-F (>= 4), or SARC-CalF (>= 11), to facilitate earlier identification of people at risk for sarcopenia. Although skeletal muscle strength and mass are both still considered fundamental to a definitive clinical diagnosis, AWGS 2019 also introduces "possible sarcopenia," defined by either low muscle strength or low physical performance only, specifically for use in primary health care or community-based health promotion, to enable earlier lifestyle interventions. Although defining sarcopenia by body mass index-adjusted muscle mass instead of height-adjusted muscle mass may predict adverse outcomes better, more evidence is needed before changing current recommendations. Lifestyle interventions, especially exercise and nutritional supplementation, prevail as mainstays of treatment. Further research is needed to investigate potential long-term benefits of lifestyle interventions, nutritional supplements, or pharmacotherapy for sarcopenia in Asians. (C) 2019 AMDA - The Society for Post-Acute and Long-Term Care Medicine.

引用

页码：300 / +

页数：10

共 118 条

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