Iron Achieves Noble Metal Reactivity and Selectivity: Highly Reactive and Enantioselective Iron Complexes as Catalysts in the Hydrosilylation of Ketones

被引：118

作者：

Bleith, Tim ^{[1
]}

Wadepohl, Hubert ^{[1
]}

Gade, Lutz H. ^{[1
]}

机构：

[1] Heidelberg Univ, Inst Anorgan Chem, D-69120 Heidelberg, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 137卷 / 07期

关键词：

ASYMMETRIC TRANSFER HYDROGENATION; PINCER LIGANDS; CARBONYL-COMPOUNDS; REDUCTION; PROTOCOL; ESTERS;

D O I：

10.1021/ja512986m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral iron alkyl and iron alkoxide complexes bearing boxmi pincers as stereodirecting ligands have been employed as catalysts for enantioselective hydrosilylation reactions with unprecedented activity and selectivity (TOF = 240 h(-1) at -40 degrees C, ee up to 99% for alkyl aryl ketones), which match the performance of previously established noble-metal-based catalysts. This shows the potential of earth-abundant metals such as iron for replacing platinum-metals without any drawbacks for the reaction design.

引用

页码：2456 / 2459

页数：4

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