IntroductionLooking into the future is difficult and sometimes hazardous. A reliable look into haemophilia treatment in 2030 should be based on history and contemporary progress as well as dilemmas. Today, the issue of inhibitors overshadows the entire haemophilia community together with lack of treatment for large parts of the world's persons with haemophilia. AimsThe aim of this paper was to provide a perspective on haemophilia treatment in 2030 and its provenance. MethodsLiterature review on history, treatment of haemophilia today as well as of emerging therapies give a base for the author's opinion on haemophilia treatment in 2030. ResultsDevelopment of haemophilia treatment has virtually exploded during the last decade and a number of new clotting factor concentrates and alternative approaches are in the pipeline. ConclusionThe collection of treatment resources that we can see on the horizon gives hope that each person with haemophilia will get the care needed in 2030. The products used will be directed by individual needs and tailored to regional and local situations.
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[1]
Aledort L M, 1979, Southeast Asian J Trop Med Public Health, V10, P280
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Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Donfield, Sharyne M.
Gomperts, Edward D.
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Childrens Hosp Los Angeles, Saban Res Inst, Los Angeles, CA 90027 USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Gomperts, Edward D.
Schwarz, John
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Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Schwarz, John
Menius, Erika D.
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Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
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Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USAWayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA
Warrier, I.
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Rajpurkar, M.
Lusher, J. M.
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Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USAWayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA
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Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Royal Free Hosp, Thrombosis Unit, London NW3 2QG, EnglandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Chowdary, P.
Lethagen, S.
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Novo Nordisk AS, Soborg, Denmark
Univ Copenhagen, Copenhagen, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Lethagen, S.
Friedrich, U.
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Novo Nordisk AS, Soborg, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Friedrich, U.
Brand, B.
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Univ Zurich Hosp, Div Hematol, CH-8091 Zurich, SwitzerlandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Brand, B.
Hay, C.
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Manchester Royal Infirm, Univ Dept Haematol, Manchester M13 9WL, Lancs, EnglandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Hay, C.
Karim, F. Abdul
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Natl Blood Ctr, Haemophilia Ctr, Kuala Lumpur, MalaysiaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Karim, F. Abdul
Klamroth, R.
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Vivantes Hosp Friedrichshain, Dept Internal Med Angiol Haemostasis & Coagulat D, Berlin, GermanyRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Klamroth, R.
Knoebl, P.
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Med Univ Vienna, Div Haematol & Haemostasis, Dept Med 1, Vienna, AustriaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Knoebl, P.
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Laffan, M.
Mahlangu, J.
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NHLS, Johannesburg, South AfricaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Mahlangu, J.
Miesbach, W.
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h-index: 0
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Univ Witwatersrand, Dept Mol Med & Haematol, Fac Hlth Sci, Johannesburg, South Africa
Hamophilie Zentrum, Zentrum Innere Med, Med Klin 3, Frankfurt, GermanyRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Miesbach, W.
Nielsen, J. Dalsgaard
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Rigshosp, Thrombosis & Haemostasis Unit, Dept Haematol, DK-2100 Copenhagen, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Nielsen, J. Dalsgaard
Martin-Salces, M.
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Hosp Univ La Paz, Dept Haematol, Madrid, SpainRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Martin-Salces, M.
Angchaisuksiri, P.
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h-index: 0
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Mahidol Univ, Ramathibodi Hosp, Fac Med, Div Hematol,Dept Med, Bangkok 10400, ThailandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
机构:
Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Donfield, Sharyne M.
Gomperts, Edward D.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Los Angeles, Saban Res Inst, Los Angeles, CA 90027 USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Gomperts, Edward D.
Schwarz, John
论文数: 0引用数: 0
h-index: 0
机构:
Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
Schwarz, John
Menius, Erika D.
论文数: 0引用数: 0
h-index: 0
机构:
Rho Inc, Dept Biostat, Chapel Hill, NC USALund Univ, Ctr Thrombosis & Haemostasis, Skane Univ Hosp, SE-20502 Malmo, Sweden
机构:
Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USAWayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA
Warrier, I.
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Rajpurkar, M.
Lusher, J. M.
论文数: 0引用数: 0
h-index: 0
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Wayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USAWayne State Univ, Childrens Hosp Michigan, Detroit Med Ctr, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA
机构:
Royal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Royal Free Hosp, Thrombosis Unit, London NW3 2QG, EnglandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Chowdary, P.
Lethagen, S.
论文数: 0引用数: 0
h-index: 0
机构:
Novo Nordisk AS, Soborg, Denmark
Univ Copenhagen, Copenhagen, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Lethagen, S.
Friedrich, U.
论文数: 0引用数: 0
h-index: 0
机构:
Novo Nordisk AS, Soborg, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Friedrich, U.
Brand, B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Zurich Hosp, Div Hematol, CH-8091 Zurich, SwitzerlandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Brand, B.
Hay, C.
论文数: 0引用数: 0
h-index: 0
机构:
Manchester Royal Infirm, Univ Dept Haematol, Manchester M13 9WL, Lancs, EnglandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Hay, C.
Karim, F. Abdul
论文数: 0引用数: 0
h-index: 0
机构:
Natl Blood Ctr, Haemophilia Ctr, Kuala Lumpur, MalaysiaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Karim, F. Abdul
Klamroth, R.
论文数: 0引用数: 0
h-index: 0
机构:
Vivantes Hosp Friedrichshain, Dept Internal Med Angiol Haemostasis & Coagulat D, Berlin, GermanyRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Klamroth, R.
Knoebl, P.
论文数: 0引用数: 0
h-index: 0
机构:
Med Univ Vienna, Div Haematol & Haemostasis, Dept Med 1, Vienna, AustriaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Knoebl, P.
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Laffan, M.
Mahlangu, J.
论文数: 0引用数: 0
h-index: 0
机构:
NHLS, Johannesburg, South AfricaRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Mahlangu, J.
Miesbach, W.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Witwatersrand, Dept Mol Med & Haematol, Fac Hlth Sci, Johannesburg, South Africa
Hamophilie Zentrum, Zentrum Innere Med, Med Klin 3, Frankfurt, GermanyRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Miesbach, W.
Nielsen, J. Dalsgaard
论文数: 0引用数: 0
h-index: 0
机构:
Rigshosp, Thrombosis & Haemostasis Unit, Dept Haematol, DK-2100 Copenhagen, DenmarkRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Nielsen, J. Dalsgaard
Martin-Salces, M.
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Univ La Paz, Dept Haematol, Madrid, SpainRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England
Martin-Salces, M.
Angchaisuksiri, P.
论文数: 0引用数: 0
h-index: 0
机构:
Mahidol Univ, Ramathibodi Hosp, Fac Med, Div Hematol,Dept Med, Bangkok 10400, ThailandRoyal Free Hosp, Katharine Dormandy Haemophilia Ctr, London NW3 2QG, England