Mechanical ventilation in COVID-19: A physiological perspective

被引:38
作者
Cronin, John N. [1 ,2 ]
Camporota, Luigi [1 ,3 ]
Formenti, Federico [1 ,4 ,5 ]
机构
[1] Kings Coll London, Sch Basic & Med Biosci, Ctr Human & Appl Physiol Sci, London SE1 1UL, England
[2] Guys & St Thomas NHS Fdn Trust, Royal Brompton & Harefield, Dept Anaesthet, London, England
[3] Guys & St Thomas NHS Fdn Trust, Intens Care Unit, London, England
[4] Univ Oxford, Nuffield Div Anaesthet, Oxford, England
[5] Univ Nebraska, Dept Biomech, Omaha, NE 68182 USA
基金
美国国家卫生研究院;
关键词
artificial; COVID-19; critical care; physiology; respiration; respiratory; respiratory distress syndrome; SARS-CoV-2; RESPIRATORY-DISTRESS-SYNDROME; FUNCTIONAL RECEPTOR; DRIVING PRESSURE; PRONE POSITION; MORTALITY; DISEASE; CORONAVIRUS; PNEUMONIA; PERFUSION; SURVIVAL;
D O I
10.1113/EP089400
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
New Findings What is the topic of this review? This review presents the fundamental concepts of respiratory physiology and pathophysiology, with particular reference to lung mechanics and the pulmonary phenotype associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent coronavirus disease 2019 (COVID-19) pneumonia.
引用
收藏
页码:683 / 693
页数:11
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