Mitral valve surgery after failed MitraClip-Operation for the inoperable?

被引:3
作者
Gerfer, Stephen [1 ]
Ivanov, Borko [1 ]
Grossmann, Clara [1 ]
Djordjevic, Ilija [1 ]
Gaisendrees, Christopher [1 ]
Eghbalzadeh, Kaveh [1 ]
Kuhn, Elmar [1 ]
Kuhn-Regnier, Ferdinand [1 ]
Mader, Navid [1 ]
Rahmanian, Parwis [1 ]
Wahlers, Thorsten [1 ]
机构
[1] Univ Hosp Cologne, Heart Ctr, Dept Cardiothorac Surg, Kerpener Str 62, D-50924 Cologne, Germany
关键词
MitraClip; mitral valve repair; mitral valve replacement; mitral valve surgery; percutaneous edge-to-edge mitral valve repair; re-do mitral valve surgery; PERCUTANEOUS REPAIR; SURGICAL REVISION; RISK; REGURGITATION; SURVIVAL; THERAPY;
D O I
10.1111/jocs.16762
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Percutaneous edge-to-edge mitral valve repair technique (MitraClip) is a widely used treatment for mitral regurgitation (MR) in patients assessed with high surgical risk or inoperability. Only limited experiences with this highest-risk patient population exist. Procedural failure for MitraClip or recurrent MR is a strong predictor of 1-year mortality. Open mitral valve surgery constitutes the last bailout for patients within this cohort. Methods This retrospective single-center cohort study analyzed 17 mitral valve surgery patients after failed MitraClip. We, therefore, analyzed a high-risk patient population (EuroSCORE II = 10 +/- 2.0) with persistent mitral valve regurgitation, which was mainly caused by detachment or dislocation of the MitraClip. Results Symptomatic patients with failed MitraClip need a convenient operation (mean time to mitral valve surgery = 23 +/- 44 days). The patient's collective showed many complex reoperations with the need for concomitant surgery. Considering the high-risk patient population, we showed an average 30-day all-cause mortality (18%, n = 3) accompanied by typical postoperative complications related to prolonged mechanical ventilation (44 +/- 48 h) and ICU stay (11 +/- 11 days), reflecting high-risk patients. Further, excellent valve-related outcomes were shown regarding adverse cardiac events (valve-related mortality 6%, n = 1) and postoperative echocardiographic results (moderate or severe paravalvular leak 6%, n = 1). Conclusion Failure of MitraClip represents a challenging situation limited by high-risk profiles of patients and limits the possibility of surgical valve repair, shown by a high rate of mitral valve replacement (94%, n = 16). Secondary surgery was associated with moderate 30-day and postdischarge outcomes. Therefore, a careful evaluation of patients undergoing MitraClip is of paramount importance.
引用
收藏
页码:4219 / 4224
页数:6
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