Synthesis and Characterization of Biologically Active Organosilicon(IV) Complexes with Schiff Bases Derived from o-aminothiophenol

被引:18
作者
Singh, Kiran [1 ]
Kumar, Yogender [1 ]
Pundir, Ram Kumar [2 ]
机构
[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India
[2] Kurukshetra Univ, Dept Microbiol, Kurukshetra 136119, Haryana, India
关键词
antimicrobial activity; o-aminothiophenol; organosilicon(IV); Schiff bases; spectral studies; DIORGANOSILICON(IV) COMPLEXES; SULFONAMIDE-IMINE; METAL-COMPLEXES; ORGANOTIN(IV); DONOR; ANTIBACTERIAL; ANTIFUNGAL; SILICON;
D O I
10.1080/15533174.2010.522646
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The synthesis and structural features of some organosilicon(IV) complexes with Schiff bases derived by condensing Substituted benzaldehyde with o-aminothiophenol have been discussed. The newly synthesized compounds have been characterized by elemental analyses, IR, 1H, 13C, and 29Si NMR spectral studies. With the help of spectral studies, penta, and hexacoordinated environments around the central silicon atoms in the 1:1 and 1:2 complexes, respectively, have been proposed. Some have been tested for the growth inhibitory activity against some bacterial and yeast strains in vitro. The antimicrobial studies revealed that the Schiff bases and some of their metal complexes possess more healing activity.
引用
收藏
页码:836 / 842
页数:7
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