Nitropyrrole natural products: isolation, biosynthesis and total synthesis

被引：25

作者：

Ding, Xiao-Bo ^{[1
]}

Brimble, Margaret A. ^{[1
,2
]}

Furkert, Daniel P. ^{[1
,2
]}

机构：

[1] Univ Auckland, Sch Chem Sci, 23 Symonds St, Auckland 1010, New Zealand

[2] Univ Auckland, Maurice Wilkins Ctr Mol Biodiscovery, Private Bag 92019, Auckland 1010, New Zealand

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2016年 / 14卷 / 24期

关键词：

PYRROLOMYCIN-B; N-OXYGENASE; STREPTOMYCES-FUMANUS; HERONAPYRROLE C; NITRO-COMPOUNDS; DIOXAPYRROLOMYCIN; ANTIBIOTICS; ENHANCEMENT; REDUCTION; NITRATION;

D O I：

10.1039/c5ob02599k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitropyrrole-containing natural products are relatively rare in nature. Known examples are limited to the beta-nitropyrrole-containing pyrrolomycins and a-nitropyrrole-containing nitropyrrolins and heronapyrroles. Their unique structures and interesting bioactivity are of ongoing interest to the chemistry community. This review describes the isolation, biological activity, biosynthesis and chemical synthesis of nitropyrrolecontaining natural products reported to date.

引用

页码：5390 / 5401

页数：12

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