Numerical investigation on dielectric material assisted microwave freeze-drying of aqueous mannitol solution

被引:56
作者
Wang, W [1 ]
Chen, GH [1 ]
机构
[1] Hong Kong Univ Sci & Technol, Dept Chem Engn, Kowloon, Hong Kong, Peoples R China
关键词
desublimation; heat and mass transfer; porous material; sublimation;
D O I
10.1081/DRT-120021870
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The dielectric material assisted microwave freeze-drying was investigated theoretically in this study. A coupled heat and mass transfer model was developed considering distributions of the temperature, ice saturation and vapor mass concentration inside the material being dried, as well as the vapor sublimation-desublimation in the frozen region. The effects of temperature and saturation on the effective conductivities were analyzed based on heat and mass flux equations. The model was solved numerically by the variable time-step finite-deference technique with two movable boundaries in an initially unsaturated porous sphere frozen from an aqueous solution of mannitol. The sintered silicon carbide (SiC) was selected as the dielectric material. The results show that dielectric material can significantly enhance microwave freeze-drying process. For case of the dielectric field strength, E=400OV/m under typical operating conditions, the drying time is 2081s, 30.1% shorter and 47.2% longer, respectively, than those for E = 2000V/m and E = 6000 V/m. The heat and mass transfer mechanisms during the drying process were discussed.
引用
收藏
页码:995 / 1017
页数:23
相关论文
共 24 条
[1]   Numerical investigation on freeze-drying of aqueous material frozen with pre-built pores [J].
Wang, Wei ;
Hu, Dapeng ;
Pan, Yanqiu ;
Chen, Guohua .
CHINESE JOURNAL OF CHEMICAL ENGINEERING, 2016, 24 (01) :116-125
[2]   Numerical investigation on freeze-drying of aqueous material frozen with pre-built pores [J].
Wei Wang ;
Dapeng Hu ;
Yanqiu Pan ;
Guohua Chen .
Chinese Journal of Chemical Engineering, 2016, 24 (01) :116-125
[3]   Theoretical study on microwave freeze-drying of an aqueous pharmaceutical excipient with the aid of dielectric material [J].
Wang, W ;
Chen, GH .
DRYING TECHNOLOGY, 2005, 23 (9-11) :2147-2168
[4]   Investigation of heat and mass transfer behavior of mannitol during vial freeze-drying [J].
Muneeshwaran, M. ;
Srinivasan, G. ;
Raja, B. ;
Wang, Chi-Chuan .
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2022, 147 (03) :2393-2404
[5]   Investigation of heat and mass transfer behavior of mannitol during vial freeze-drying [J].
M. Muneeshwaran ;
G. Srinivasan ;
B. Raja ;
Chi-Chuan Wang .
Journal of Thermal Analysis and Calorimetry, 2022, 147 :2393-2404
[6]   Investigation of freeze-drying sublimation rates using a freeze-drying microbalance technique [J].
Xiang, J ;
Hey, JM ;
Liedtke, V ;
Wang, DQ .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2004, 279 (1-2) :95-105
[7]   Microwave freeze-drying of coffee solution frozen with initial pores assisted by wave-absorbing medium [J].
Zhang, Shuo ;
Pan, Yanqiu ;
Wang, Wei ;
Lin, Runze ;
Zhang, Shuwei .
DRYING TECHNOLOGY, 2023, 41 (03) :419-433
[8]   Investigation to Increase the Drying Rate of the Freeze-Drying [J].
Pliske, Roland ;
Mueller, Ulrich ;
Kohlus, Reinhard .
CHEMIE INGENIEUR TECHNIK, 2015, 87 (07) :1006-1010
[9]   Effect of dielectric material on microwave freeze drying of skim milk [J].
Wang, W ;
Chen, GH ;
Gao, FR .
DRYING TECHNOLOGY, 2005, 23 (1-2) :317-340
[10]   Sublimation-condensation phenomenon in microwave freeze-drying [J].
Wang, ZH ;
Shi, MH .
SCIENCE IN CHINA SERIES E-TECHNOLOGICAL SCIENCES, 1998, 41 (03) :321-329