Current Therapeutic Options for Heart Failure in Elderly Patients

被引：10

作者：

Guerra, F. ^{[1
]}

Brambatti, M. ^{[1
]}

Matassini, M. V. ^{[1
]}

Capucci, A. ^{[1
]}

机构：

[1] Marche Polytech Univ, Univ Hosp Ospedali Riuniti, Dept Biomed Sci & Publ Hlth, Cardiol & Arrhythmol Clin, Ancona, Italy

来源：

BIOMED RESEARCH INTERNATIONAL | 2017年 / 2017卷

关键词：

VENTRICULAR ASSIST DEVICE; CARDIAC-RESYNCHRONIZATION THERAPY; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; LUNG TRANSPLANTATION GUIDELINES; MECHANICAL CIRCULATORY SUPPORT; CONVERTING-ENZYME-INHIBITOR; REDUCED EJECTION FRACTION; INTERMACS ANNUAL-REPORT; MYOCARDIAL-INFARCTION; PRIMARY PREVENTION;

D O I：

10.1155/2017/1483873

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Heart failure (HF) is a major and growing public health problem with high morbidity and mortality (Ponikowski et al., 2016). It affects 1-2% of the general population in developed countries, and the average age at diagnosis is 76 years. Because of a better management of acute phase and comorbidities, HF incidence is increasing in elderly patients, with a prevalence rising to 10% among people aged 65 years or older (Mozaffarian et al., 2014). Therefore, a substantial number of elderly patients need to be treated. However, because of clinical trial exclusion criteria or coexisting comorbidities, currently recommended therapies are widely based on younger population with a much lower mean age. In this review, we will focus on available pharmacological, electrical, and mechanical therapies, underlining pros, cons, and practical considerations of their use in this specific patient population.

引用

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