Forward-time simulations of non-random mating populations using simuPOP

被引:48
作者
Peng, Bo [1 ]
Amos, Christopher I. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA
关键词
D O I
10.1093/bioinformatics/btn179
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Computer simulations play an important role in studies of non-random mating populations. Because of implementation difficulties, only very limited types of non-random mating schemes are provided in the currently available simulation programs. Starting with version 0.8.5, simuPOP provides a few mating schemes that can be used to simulate arbitrary non-random mating models. This article describes the concepts and methods behind these mating schemes and demonstrates their uses in a few examples, including partial self-mating, positive assortative mating, non-random outbreeding, and simulation of overlapping generations in age-structured populations.
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收藏
页码:1408 / 1409
页数:2
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