EFFECT OF FUMONISIN B1 ON LYMPHATIC ORGANS IN BROILER CHICKENS - PATHOMORPHOLOGY

被引：0
|
作者：
Todorova, Katerina Stanimirova [1 ]
Kril, Anton Ivanov [1 ]
Dimitrov, Peter Stoykov [1 ]
Gardeva, Elena Georgieva [1 ]
Toshkova, Reneta Aleksandrova [1 ]
Tasheva, Yuliana Rumenova [2 ]
Petrichev, Metody Hristov [2 ]
Russev, Russy Vladimirov [1 ]
机构：
[1] BAS, Pathol & Anthropol Museum, Inst Expt Morphol, Sofia 1113, Bulgaria
[2] Natl Diagnost & Res Vet Med Inst, Sofia 1113, Bulgaria
来源：
BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY | 2011年 / 55卷 / 04期
关键词：
broiler chickens; lymphatic organs; fumonisin B1; pathomorphology; SALMONELLA-GALLINARUM INFECTION; PROLIFERATUM CULTURE MATERIAL; PATHOLOGICAL-CHANGES; B-1; FUSARIUM; IMMUNE; TOXICITY;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The purpose of this study was to establish the pathomorphological alterations in the lymphatic organs of broiler chickens fed forages containing fumonisin B1 (FB1), known to cause immunodeficiency. The birds were treated with mycotoxin isolated from corn contaminated with F. verticilloides (moniliforme). Apoptotic and necrotic changes were recorded,under light and electron microscopes. Significant morphological alterations such as focal necrosis and an increased number of apoptotic lymphocytes and epithelial cells were found mainly in the thymus and spleen, while the bursa Fabricii was less affected. It can be concluded that FBI causes in vivo suppression of development, differentiation, and function of the lymphoid cells and the stromal epithelial reticular cells, and activates the processes leading to cell death in organs of the immune system of chickens.
引用
收藏
页码：801 / 805
页数：5
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