DBU-Mediated Efficient Synthesis of Diaryl Ethynes and Enynes from 1,1-Dibromoalkenes at Room Temperature

被引：6
|
作者：
Thummala, Yadagiri [1 ]
Morri, Ashok K. [1 ]
Karunakar, Galla V. [1 ]
Doddi, Venkata Ramana [1 ,2 ]
机构：
[1] CSIR IICT, Organ & Biomol Chem Div, Hyderabad 500007, Andhra Pradesh, India
[2] Cent Univ Jammu, Dept Chem & Chem Sci, Jammu, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 2018卷 / 45期
关键词：
Bicyclic amidine; DBU; 1,1-Dibromoalkene; Disubstituted alkyne; Enynes; CATALYZED COUPLING REACTIONS; INTERNAL ALKYNES; 1,1-DIBROMO-1-ALKENES; ARYL; COMBINATION; REACTIVITY; SYSTEMS;
D O I：
10.1002/ejoc.201801143
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 1,1-dibromoalkenes and aryl iodides in the presence of DBU and a Pd-II/Cu-I catalytic system afforded diaryl alkynes and enynes at ambient temperature. Control experiments demonstrated the essential ligand role of DBU in this transformation. The unusual stability of the key catalyst, Pd-0(DBU)(2), allowed it to be characterized by HRMS analysis.
引用
收藏
页码：6280 / 6285
页数：6
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