Activity-dependent plasticity and spinal cord stimulation for motor recovery following spinal cord injury

被引：20

作者：

Samejima, Soshi ^{[1
]}

Henderson, Richard ^{[2
,3
,4
]}

Pradarelli, Jared ^{[4
]}

Mondello, Sarah E. ^{[4
]}

Moritz, Chet T. ^{[3
,4
,5
,6
,7
]}

机构：

[1] Univ British Columbia, Fac Med, Int Collaborat Repair Discoveries, Vancouver, BC, Canada

[2] Univ British Columbia, Dept Med, Div Phys Med & Rehabil, Vancouver, BC, Canada

[3] Univ Washington, Dept Elect & Comp Engn, Seattle, WA USA

[4] Univ Washington, Dept Rehabil Med, Seattle, WA USA

[5] Ctr Neurotechnol, Seattle, WA USA

[6] Univ Washington, Dept Physiol & Biophys, Seattle, WA USA

[7] Univ Washington, Dept Elect & Comp Engn, Seattle, WA 98195 USA

来源：

EXPERIMENTAL NEUROLOGY | 2022年 / 357卷

基金：

美国国家科学基金会;

关键词：

Spinal cord injury; activity -dependent plasticity; spinal cord stimulation; motor function; closed -loop stimulation; EPIDURAL ELECTRICAL-STIMULATION; CELLULAR INFLAMMATORY RESPONSE; OSCILLATING FIELD STIMULATION; CENTRAL-NERVOUS-SYSTEM; SOLEUS H-REFLEX; AXONAL REGENERATION; NEURAL PLASTICITY; NEURITE OUTGROWTH; DORSAL-HORN; TRANSCUTANEOUS STIMULATION;

D O I：

10.1016/j.expneurol.2022.114178

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Spinal cord injuries lead to permanent physical impairment despite most often being anatomically incomplete disruptions of the spinal cord. Remaining connections between the brain and spinal cord create the potential for inducing neural plasticity to improve sensorimotor function, even many years after injury. This narrative review provides an overview of the current evidence for spontaneous motor recovery, activity-dependent plasticity, and interventions for restoring motor control to residual brain and spinal cord networks via spinal cord stimulation. In addition to open-loop spinal cord stimulation to promote long-term neuroplasticity, we also review a more targeted approach: closed-loop stimulation. Lastly, we review mechanisms of spinal cord neuromodulation to promote sensorimotor recovery, with the goal of advancing the field of rehabilitation for physical impairments following spinal cord injury.

引用

页数：12

共 231 条

[1] Traumatic spinal cord injury [J].

Ahuja, Christopher S. ;

Wilson, Jefferson R. ;

Nori, Satoshi ;

Kotter, Mark R. N. ;

Druschel, Claudia ;

Curt, Armin ;

Fehlings, Michael G. .

NATURE REVIEWS DISEASE PRIMERS, 2017, 3

[2] Restoration of reaching and grasping movements through brain-controlled muscle stimulation in a person with tetraplegia: a proof-of-concept demonstration [J].

Ajiboye, A. Bolu ;

Willett, Francis R. ;

Young, Daniel R. ;

Memberg, William D. ;

Murphy, Brian A. ;

Miller, Jonathan P. ;

Walter, Benjamin L. ;

Sweet, Jennifer A. ;

Hoyen, Harry A. ;

Keith, Michael W. ;

Peckham, P. Hunter ;

Simeral, John D. ;

Donoghue, John P. ;

Hochberg, Leigh R. ;

Kirsch, Robert F. .

LANCET, 2017, 389 (10081) :1821-1830

[3] Neurogenic bladder in spinal cord injury patients [J].

Al Taweel, Waleed ;

Seyam, Raouf .

RESEARCH AND REPORTS IN UROLOGY, 2015, 7 :85-99

[4] Reversing 21 years of chronic paralysis via non-invasive spinal cord neuromodulation: a case study [J].

Alam, Monzurul ;

Ling, Yan To ;

Wong, Arnold Y. L. ;

Zhong, Hui ;

Edgerton, Victor Reggie ;

Zheng, Yong-Ping .

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2020, 7 (05) :829-838

[5] Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms [J].

Alizadeh, Arsalan ;

Dyck, Scott Matthew ;

Karimi-Abdolrezaee, Soheila .

FRONTIERS IN NEUROLOGY, 2019, 10

[6] Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury [J].

Angeli, Claudia A. ;

Boakye, Maxwell ;

Morton, Rebekah A. ;

Vogt, Justin ;

Benton, Kristin ;

Chen, Yangshen ;

Ferreira, Christie K. ;

Harkema, Susan J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (13) :1244-1250

[7] Altering spinal cord excitability enables voluntary movements after chronic complete paralysis in humans [J].

Angeli, Claudia A. ;

Edgerton, V. Reggie ;

Gerasimenko, Yury P. ;

Harkema, Susan J. .

BRAIN, 2014, 137 :1394-1409

[8] Connecting neuronal circuits for movement Dedicated neuronal circuits mediate execution, choice, and coordination of body action [J].

Arber, Silvia ;

Costa, Rui M. .

SCIENCE, 2018, 360 (6396) :1403-1404

[9] Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion [J].

Asboth, Leonie ;

Friedli, Lucia ;

Beauparlant, Janine ;

Martinez-Gonzalez, Cristina ;

Anil, Selin ;

Rey, Elodie ;

Baud, Laetitia ;

Pidpruzhnykova, Galyna ;

Anderson, Mark A. ;

Shkorbatova, Polina ;

Batti, Laura ;

Pages, Stephane ;

Kreider, Julie ;

Schneider, Bernard L. ;

Barraud, Quentin ;

Courtine, Gregoire .

NATURE NEUROSCIENCE, 2018, 21 (04) :576-+

[10] Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers [J].

Ballermann, M ;

Fouad, K .

EUROPEAN JOURNAL OF NEUROSCIENCE, 2006, 23 (08) :1988-1996

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