Diagnostic applications of Raman spectroscopy

被引：172

作者：

Tu, Qiang ^{[2
]}

Chang, Chang ^{[1
,2
]}

机构：

[1] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA

[2] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA

来源：

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE | 2012年 / 8卷 / 05期

关键词：

Raman spectroscopy; SERS; Cancer diagnosis; Transplant rejection; WALLED CARBON NANOTUBES; IN-VIVO; BREAST-CANCER; ALLOGRAFT-REJECTION; SILVER NANOPARTICLES; DELIVERY-SYSTEMS; DRUG-DELIVERY; T-LYMPHOCYTES; LIVING MICE; SERS;

D O I：

10.1016/j.nano.2011.09.013

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Raman spectroscopy has been widely used in various fields of science. It has been successfully utilized to qualitatively and quantitatively determine the molecular compositions of solid, liquid, and gaseous samples. This review focuses on the diagnostic applications of Raman spectroscopy in the past 5 years, with specific emphasis on transplant allograft rejection and cancer detections. First we introduce the principle of Raman spectroscopy and associated surface enhancement techniques. Various recent biomedical and clinical applications of Raman spectroscopy are then reviewed in detail. Finally, we present the experimental and analytical techniques required to implement Raman spectroscopy in a laboratory.

引用

页码：545 / 558

页数：14

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