N′-(2-Hydroxybenzylidene)-3-Methylbenzohydrazide and its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity

被引：3

作者：

Zhao, Hui ^{[1
,2
]}

Tan, Xiang-Peng ^{[1
,2
]}

Peng, Qi-An ^{[1
,2
]}

Shi, Cong-Zhong ^{[3
]}

Zhao, Yi-Fei ^{[3
]}

Cui, Yong-Ming ^{[3
]}

机构：

[1] Wuhan Text Univ, Sch Environm Engn, Wuhan 430073, Peoples R China

[2] Minist Educ, Engn Res Ctr Clean Prod Text Dyeing & Printing, Wuhan 430200, Peoples R China

[3] Wuhan Text Univ, Natl Local Joint Engn Lab Adv Text Proc & Clean P, Wuhan 430200, Peoples R China

来源：

ACTA CHIMICA SLOVENICA | 2020年 / 67卷 / 02期

关键词：

Hydrazone; copper complex; crystal structure; biological activity; JACK-BEAN UREASE; HELICOBACTER-PYLORI UREASE; OXIDOVANADIUM(V) COMPLEXES; SPECTROSCOPIC CHARACTERIZATION; ANTIBACTERIAL ACTIVITIES; CYTOTOXIC ACTIVITIES; INHIBITORY-ACTIVITY; HYDRAZONE; COBALT(III); LIGANDS;

D O I：

10.17344/acsi.2019.5644

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]center dot CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques. The complex is a thiocyanato-coordinated copper(II) species. The Cu atom in the complex is in square planar geometry. The complex is a promising urease inhibitor.

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页码：638 / 643

页数：6

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