Recent Developments in Antimicrobial Polymers: A Review

被引:163
作者
Santos, Madson R. E. [1 ]
Fonseca, Ana C. [1 ]
Mendona, Patricia V. [1 ]
Branco, Rita [2 ]
Serra, Armenio C. [1 ]
Morais, Paula V. [2 ]
Coelho, Jorge F. J. [1 ]
机构
[1] Univ Coimbra, Dept Chem Engn, CEMUC, P-3030790 Coimbra, Portugal
[2] Univ Coimbra, Dept Life Sci, CEMUC, P-3001401 Coimbra, Portugal
关键词
antimicrobial polymers; biocide polymers; multidrug resistant microbes; LAYER-BY-LAYER; QUATERNARY AMMONIUM; ANTIBACTERIAL ACTIVITY; CHITOSAN DERIVATIVES; PHOTODYNAMIC INACTIVATION; ANTIBIOTIC-RESISTANCE; METHACRYLATE POLYMERS; TRIMETHYL CHITOSAN; DELIVERY-SYSTEMS; ZNO PARTICLES;
D O I
10.3390/ma9070599
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Antimicrobial polymers represent a very promising class of therapeutics with unique characteristics for fighting microbial infections. As the classic antibiotics exhibit an increasingly low capacity to effectively act on microorganisms, new solutions must be developed. The importance of this class of materials emerged from the uncontrolled use of antibiotics, which led to the advent of multidrug-resistant microbes, being nowadays one of the most serious public health problems. This review presents a critical discussion of the latest developments involving the use of different classes of antimicrobial polymers. The synthesis pathways used to afford macromolecules with antimicrobial properties, as well as the relationship between the structure and performance of these materials are discussed.
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页数:33
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