Skin biopsy-proven flecainide-induced neuropathy

被引：7
|
作者：
Burakgazi, Ahmet Z. [2 ]
Polydefkis, Michael [1 ]
Hoeke, Ahmet [1 ]
机构：
[1] Johns Hopkins Sch Med, Dept Neurol, Baltimore, MD 21205 USA
[2] George Washington Univ, Dept Neurol, Washington, DC USA
来源：
MUSCLE & NERVE | 2012年 / 45卷 / 01期
关键词：
flecainide; peripheral neuropathy; skin biopsy; toxic neuropathy; potassium channel; PARANOID PSYCHOSIS; TOXICITY; NEURONS; CHANNEL;
D O I：
10.1002/mus.22239
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Flecainide acetate is a classic Ic antiarrhythmic agent used to treat a variety of cardiac arrhythmias. Non-cardiac side effects usually affect the central nervous system. Few case reports of possible flecainide-induced peripheral neuropathy have been reported. We report this unique case in that flecainide-induced sensory neuropathy was confirmed with skin biopsy, and subsequent improvement of neuropathy was documented with assessment of intraepidermal nerve fiber density in a repeat nerve biopsy. Muscle Nerve 45: 144146, 2011
引用
收藏
页码：144 / 146
页数：3
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