Skin biopsy-proven flecainide-induced neuropathy

被引：7

作者：

Burakgazi, Ahmet Z. ^{[2
]}

Polydefkis, Michael ^{[1
]}

Hoeke, Ahmet ^{[1
]}

机构：

[1] Johns Hopkins Sch Med, Dept Neurol, Baltimore, MD 21205 USA

[2] George Washington Univ, Dept Neurol, Washington, DC USA

来源：

MUSCLE & NERVE | 2012年 / 45卷 / 01期

关键词：

flecainide; peripheral neuropathy; skin biopsy; toxic neuropathy; potassium channel; PARANOID PSYCHOSIS; TOXICITY; NEURONS; CHANNEL;

D O I：

10.1002/mus.22239

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Flecainide acetate is a classic Ic antiarrhythmic agent used to treat a variety of cardiac arrhythmias. Non-cardiac side effects usually affect the central nervous system. Few case reports of possible flecainide-induced peripheral neuropathy have been reported. We report this unique case in that flecainide-induced sensory neuropathy was confirmed with skin biopsy, and subsequent improvement of neuropathy was documented with assessment of intraepidermal nerve fiber density in a repeat nerve biopsy. Muscle Nerve 45: 144146, 2011

引用

页码：144 / 146

页数：3

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