A mouse is not a man: Should we abandon murine models in critical care research?

被引:2
作者
Wagner, Katja [1 ]
Calzia, Enrico [1 ]
Georgieff, Michael [1 ]
Radermacher, Peter [1 ]
Wagner, Florian [1 ]
机构
[1] Univ Ulm Klinikum, Anasthesiol Klin, D-7900 Ulm, Germany
关键词
hydrogen sulfide; nonshivering thermogenesis; sheep; suspended animation; swine; INHALED HYDROGEN-SULFIDE; ANIMATION-LIKE STATE; NITRIC-OXIDE; INDUCED HYPOMETABOLISM; SEPSIS; MICE; HYPOTHERMIA; MECHANISMS; PROTECTS; SHOCK;
D O I
10.1097/CCM.0b013e318224995d
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:2371 / 2373
页数:3
相关论文
共 29 条
  • [1] Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock
    Barth, E
    Radermacher, P
    Thiemermann, C
    Weber, S
    Georgieff, M
    Albuszies, G
    [J]. CRITICAL CARE MEDICINE, 2006, 34 (02) : 307 - 313
  • [2] Bauer M, 2006, CRIT CARE MED, V34, P912
  • [3] Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice
    Baumgart, Katja
    Wagner, Florian
    Groeger, Michael
    Weber, Sandra
    Barth, Eberhard
    Vogt, Josef A.
    Wachter, Ulrich
    Huber-Lang, Markus
    Knoeferl, Markus W.
    Albuszies, Gerd
    Georgieff, Michael
    Asfar, Pierre
    Szabo, Csaba
    Calzia, Enrico
    Radermacher, Peter
    Simkova, Vladislava
    [J]. CRITICAL CARE MEDICINE, 2010, 38 (02) : 588 - 595
  • [4] Myocardial dysfunction in sepsis: no role for NO?
    Belcher, E
    Mitchell, J
    Evans, T
    [J]. HEART, 2002, 87 (06) : 507 - 509
  • [5] H2S induces a suspended animation-like state in mice
    Blackstone, E
    Morrison, M
    Roth, MB
    [J]. SCIENCE, 2005, 308 (5721) : 518 - 518
  • [6] Suspended animation-like state protects mice from lethal hypoxia
    Blackstone, Eric
    Roth, Mark B.
    [J]. SHOCK, 2007, 27 (04): : 370 - 372
  • [7] Hydrogen Sulfide-Induced Hypometabolism Prevents Renal Ischemia/Reperfusion Injury
    Bos, Eelke M.
    Leuvenink, Henri G. D.
    Snijder, Pauline M.
    Kloosterhuis, Niels J.
    Hillebrands, Jan-Luuk
    Leemans, Jaklien C.
    Florquin, Sandrine
    van Goor, Harry
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 20 (09): : 1901 - 1905
  • [8] Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic and vasomotor effects
    Derwall, Matthias
    Francis, Roland C. E.
    Kida, Kotaro
    Bougaki, Masahiko
    Crimi, Ettore
    Adrie, Christophe
    Zapol, Warren M.
    Ichinose, Fumito
    [J]. CRITICAL CARE, 2011, 15 (01):
  • [9] INTRAVENOUS HYDROGEN SULFIDE DOES NOT INDUCE HYPOTHERMIA OR IMPROVE SURVIVAL FROM HEMORRHAGIC SHOCK IN PIGS
    Drabek, Tomas
    Kochanek, Patrick M.
    Stezoski, Jason
    Wu, Xianren
    Bayir, Huelya
    Morhard, Ryan C.
    Stezoski, S. William
    Tisherman, Samuel A.
    [J]. SHOCK, 2011, 35 (01): : 67 - 73
  • [10] Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury
    Esechie, Aimalohi
    Enkhbaatar, Perenlei
    Traber, Daniel L.
    Jonkam, Collette
    Lange, Matthias
    Hamahata, Atsumori
    Djukom, Clarisse
    Whorton, Elbert B.
    Hawkins, Hal K.
    Traber, Lillian D.
    Szabo, Csaba
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 2009, 158 (06) : 1442 - 1453