Alcohol associated liver disease 2020: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)

被引:24
作者
Addolorato, Giovanni [1 ,2 ]
Abenavoli, Ludovico [3 ]
Dallio, Marcello [4 ]
Federico, Alessandro [4 ]
Germani, Giacomo [5 ]
Gitto, Stefano [6 ]
Leandro, Gioacchino [7 ]
Loguercio, Carmelina [4 ]
Marra, Fabio [6 ,8 ]
Stasi, Elisa [7 ]
机构
[1] Univ Cattolica Sacro Cuore, Alcohol Use Disorder Unit, Div Internal Med, Gastroenterol & Hepatol Unit,A Gemelli Hosp, Rome, Italy
[2] Agostino Gemelli Hosp Fdn IRCCS, Rome, Italy
[3] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Catanzaro, Italy
[4] Univ Campania Luigi Vanvitelli, Dept Precis Med, Naples, Italy
[5] Padova Univ Hosp, Multivisceral Transplant Unit, Dept Surg Oncol & Gastroenterol, Padua, Italy
[6] Univ Florence, Dept Expt & Clin Med, Florence, Italy
[7] Natl Inst Gastroenterol S De Bellis Res Hosp, Castellana Grotte, Italy
[8] Univ Florence, Res Ctr Denothe, Florence, Italy
关键词
Alcohol abstinence; Alcohol associated liver disease; Alcoholic hepatitis; Alcohol use disorder; Binge drinking; Liver damage; Liver transplantation; Psychosocial interventions; Treatment; PANCREATIC STELLATE CELLS; RANDOMIZED DOUBLE-BLIND; BINGE DRINKING; FATTY LIVER; WERNICKES ENCEPHALOPATHY; TRANSIENT ELASTOGRAPHY; HEPATIC HEMODYNAMICS; GENE-EXPRESSION; STRESS-RESPONSE; SCORING SYSTEM;
D O I
10.1016/j.dld.2019.12.008
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Alcohol use disorder which includes alcohol abuse and dependence represents one of the leading risk factors for premature mortality in Europe and it is responsible of over 200 conditions, including neuropsychiatric disorders, chronic diseases, cancers and accidents leading to permanent disability. Alcohol use disorder represents the most common cause of liver damage in the Western world, with a wide spectrum of diseases ranging from steatosis, steatohepatitis, fibrosis, cirrhosis and cancer. The present clinical practice guidelines by the Italian Association for the Study of the Liver (AISF) are focused on the current knowledge about epidemiology, pathophysiology, clinical features, diagnosis and treatment of alcohol associated liver disease, aiming to provide practical recommendations on the management of this complex pathological condition. (C) 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:374 / 391
页数:18
相关论文
共 185 条
  • [1] Elastography in hepatology
    Abenavoli, Ludovico
    Corpechot, Christophe
    Poupon, Raoul
    [J]. CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2007, 21 (12) : 839 - 842
  • [2] Binge drinking and the risk of liver events: A population-based cohort study
    Aberg, Fredrik
    Helenius-Hietala, Jaana
    Puukka, Pauli
    Jula, Antti
    [J]. LIVER INTERNATIONAL, 2017, 37 (09) : 1373 - 1381
  • [3] Baclofen in the treatment of alcohol withdrawal syndrome: A comparative study vs diazepam
    Addolorato, G
    Leggio, L
    Abenavoli, L
    Agabio, R
    Caputo, F
    Capristo, E
    Colombo, G
    Gessa, GL
    Gasbarrini, G
    [J]. AMERICAN JOURNAL OF MEDICINE, 2006, 119 (03) : 276.e13 - 276.e18
  • [4] Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study
    Addolorato, Giovanni
    Leggio, Lorenzo
    Ferrulli, Anna
    Cardone, Silvia
    Vonghia, Luisa
    Mirijello, Antonio
    Abenavoli, Ludovico
    D'Angelo, Cristina
    Caputo, Fabio
    Zambon, Antonella
    Haber, Paul S.
    Gasbarrini, Giovanni
    [J]. LANCET, 2007, 370 (9603) : 1915 - 1922
  • [5] Diagnosis and Management of Alcohol Use Disorder in Patients with Liver Disease: Lights and Shadows
    Addolorato, Giovanni
    Vassallo, Gabriele A.
    Mirijello, Antonio
    Gasbarrini, Antonio
    [J]. NEUROTHERAPEUTICS, 2020, 17 (01) : 127 - 141
  • [6] Binge Drinking among adolescents is related to the development of Alcohol Use Disorders: results from a Cross-Sectional Study
    Addolorato, Giovanni
    Vassallo, Gabriele A.
    Antonelli, Giulio
    Antonelli, Mariangela
    Tarli, Claudia
    Mirijello, Antonio
    Agyei-Nkansah, Adwoa
    Mentella, Maria C.
    Ferrarese, Daniele
    Mora, Vincenzina
    Barbara, Marco
    Maida, Marcello F.
    Camma, Calogero
    Gasbarrini, Antonio
    [J]. SCIENTIFIC REPORTS, 2018, 8
  • [7] Treatment of alcohol use disorders in patients with alcoholic liver disease
    Addolorato, Giovanni
    Mirijello, Antonio
    Barrio, Pablo
    Gual, Antoni
    [J]. JOURNAL OF HEPATOLOGY, 2016, 65 (03) : 618 - 630
  • [8] Liver Transplantation for Alcoholic Liver Disease
    Addolorato, Giovanni
    Bataller, Ramon
    Burra, Patrizia
    DiMartini, Andrea
    Graziadei, Ivo
    Lucey, Michael R.
    Mathurin, Philippe
    O'Grady, John
    Pageaux, Georges
    Berenguer, Marina
    [J]. TRANSPLANTATION, 2016, 100 (05) : 981 - 987
  • [9] Liver Transplantation in Alcoholic Patients: Impact of an Alcohol Addiction Unit Within a Liver Transplant Center
    Addolorato, Giovanni
    Mirijello, Antonio
    Leggio, Lorenzo
    Ferrulli, Anna
    D'Angelo, Cristina
    Vassallo, Gabriele
    Cossari, Anthony
    Gasbarrini, Giovanni
    Landolfi, Raffaele
    Agnes, Salvatore
    Gasbarrini, Antonio
    [J]. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2013, 37 (09) : 1601 - 1608
  • [10] Management of Alcohol Dependence in Patients with Liver Disease
    Addolorato, Giovanni
    Mirijello, Antonio
    Leggio, Lorenzo
    Ferrulli, Anna
    Landolfi, Raffaele
    [J]. CNS DRUGS, 2013, 27 (04) : 287 - 299