Selective Functionalization of Aromatic C(sp2)-H Bonds in the Presence of Benzylic C(sp3)-H Bonds by Electron-Deficient Carbenoids Generated from 4-Acyl-1-Sulfonyl-1,2,3-Triazoles

被引：49

作者：

Miura, Tomoya ^{[1
]}

Zhao, Qiang ^{[1
]}

Murakami, Masahiro ^{[1
]}

机构：

[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Kyoto 6158510, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2017年 / 56卷 / 52期

关键词：

arenes; C-H insertion; carbenoids; reaction mechanisms; rhodium; C-H FUNCTIONALIZATION; RHODIUM-CATALYZED TRANSANNULATION; ALPHA-DIAZOCARBONYL COMPOUNDS; CHIRAL DIRHODIUM CATALYSTS; DIAZO-COMPOUNDS; SULFONYL AZIDES; GOLD CATALYSIS; INSERTION; DIAZOESTERS; ARENES;

D O I：

10.1002/anie.201709384

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A rhodium(II)-catalyzed reaction of newly prepared 4-acyl-1-sulfonyl-1,2,3-triazoles with benzene, and its derivatives, is investigated. Acceptor/acceptor carbenoids generated from 4-acyltriazoles undergo selective insertion at aromatic C(sp(2))-H bonds in the presence of benzylic C(sp(3))-H bonds to produce N-sulfonylenaminones.

引用

收藏

页码：16645 / 16649

页数：5

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