Proportion of neuropathic pain in the back region in chronic low back pain patients -a multicenter investigation

被引:4
作者
Li, Jun [1 ]
He, Jing [1 ]
Li, Hu [2 ]
Fan, Bi-Fa [3 ]
Liu, Bo-Tao [3 ]
Mao, Peng [3 ]
Jin, Yi [4 ]
Cheng, Zhu-Qiang [4 ]
Zhang, Ting-Jie [1 ]
Zhong, Zhi-Fang [1 ]
Li, Si-Ji [1 ]
Zhu, Sai-Nan [5 ]
Feng, Yi [1 ]
机构
[1] Peking Univ, Peoples Hosp, Dept Pain Med, Beijing 100044, Peoples R China
[2] Peking Univ, Peoples Hosp, Arthrit Clin & Res Ctr, Beijing 100044, Peoples R China
[3] China Japan Friendship Hosp, Dept Pain Med, Beijing 100029, Peoples R China
[4] Jinling Hosp, Pain Med Ctr, Dept Anesthesiol, Nanjing 210002, Jiangsu, Peoples R China
[5] Peking Univ, Hosp 1, Dept Epidemiol, Beijing 100034, Peoples R China
关键词
LEEDS ASSESSMENT; COMPONENTS; PREVALENCE; GABAPENTIN; MECHANISMS; SYMPTOMS; BURDEN;
D O I
10.1038/s41598-018-33832-x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Neuropathy can contribute to low back pain (LBP) in the region of the back. Our study investigated the proportion of neuropathic pain (NP) in low back region in chronic LBP patients from multicenter and clinics in China and identified associated factors. Assessment was made using a questionnaire and the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS, only tested in low back region), as well as Quantitative Sensory Testing (QST, merely applied to the low back region), the Hospital Anxiety and Depression Scale (HADS) and the Oswestry Disability Index (ODI). Our questionnaire collected demographic information, behavioral habits and medical records. 2116 outpatients over 18 years old complaining of LBP lasting more than 3 months were enrolled in this study. The NP proportion in low back region in chronic LBP patients was 2.8%. Multivariable logistic regression analysis showed that histories of lumbar surgery, abdominal or pelvic surgery, and drinking alcohol were independent positive predictors for LBP of predominantly neuropathic origin (LBNPO), while history of low back sprain and frequently carrying weight as independent negative predictor. Using these parameters may help the identification of patients with chronic LBP likely to develop NP leading to improved treatment outcomes.
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页数:7
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