Pamidronate treatment of hypercalcemia caused by vitamin D toxicity

被引：0

作者：

Chatterjee, Manjula ^{[1
]}

Speiser, Phyllis W. ^{[1
,2
]}

机构：

[1] Schneider Childrens Hosp, Div Pediat Endocrinol, New Hyde Pk, NY 11040 USA

[2] NYU, Sch Med, Dept Pediat, New York, NY USA

来源：

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | 2007年 / 20卷 / 11期

关键词：

bisphosphonate; pamidronate; therapy; hypercalcemia; ergocalciferol (vitamin D) administration; dosage; toxicity;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a 16 month-old previously healthy boy with refractory hypercalcemia due to an overdose of an over-the-counter vitamin supplement. The patient presented to the emergency department with a few weeks' history of irritability, constipation and intermittent vomiting. His serum calcium was found to be 18 mg/dl. He was first treated with intravenous fluids, furosemide and glucocorticoids without significant improvement, but became eucalcemic within 24 hours after receiving a single dose of pamidronate. This case highlights the potential danger of high dose vitamin supplements in children, and the salutary effects of treatment with bisphosphonate.

引用

页码：1241 / 1248

页数：8

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