[1] Inst Gustave Roussy, INSERM, Unit 848, F-94805 Villejuif, France
[2] Fac Paris Sud Univ Paris 11, F-94805 Villejuif, France
[3] INSERM, U580, F-75015 Paris, France
[4] Univ Paris 05, Fac Med Rene Descartes, F-75015 Paris, France
[5] Inst Gustave Roussy, INSERM, U805, F-94805 Villejuif, France