Long-term follow-up of subcutaneous versus intravenous bortezomib during induction therapy for newly diagnosed multiple myeloma treated within the GMMG-MM5 Phase III Trial

被引：4

作者：

Salwender, Hans ^{[1
]}

Elmaagacli, Ahmet ^{[2
]}

Merz, Maximilian ^{[3
]}

Miah, Kaya ^{[4
]}

Benner, Axel ^{[4
]}

Haenel, Mathias ^{[5
]}

Jehn, Christian ^{[2
]}

Mai, Elias K. ^{[6
]}

Bertsch, Uta ^{[6
,7
]}

Blau, Igor W. ^{[8
]}

Scheid, Christof ^{[9
]}

Hose, Dirk ^{[10
]}

Seckinger, Anja ^{[10
]}

Jauch, Anna ^{[11
]}

Raab, Marc S. ^{[6
]}

Luntz, Steffen P. ^{[12
]}

Besemer, Britta ^{[13
]}

Munder, Markus ^{[14
]}

Brossart, Peter ^{[15
]}

Fuhrmann, Stephan ^{[16
]}

Lindemann, Hans-Walter ^{[17
]}

Weisel, Katja ^{[18
]}

Duerig, Jan ^{[19
]}

Goldschmidt, Hartmut ^{[6
,7
]}

机构：

[1] AK Altona, Asklepios Tumorzentrum Hamburg, Hamburg, Germany

[2] Allgemein Krankenhaus St Georg, Dept Hematol Oncol & Stem Cell Transplantat, Hamburg, Germany

[3] Univ Hosp Leipzig, Dept Hematol Celltherapy & Hemostaseol, Leipzig, Germany

[4] German Canc Res Ctr, Div Biostat, Heidelberg, Germany

[5] Klinikum Chemnitz, Chemnitz, Germany

[6] Univ Heidelberg Hosp, Dept Hematol Oncol & Rheumatol, Heidelberg, Germany

[7] Natl Ctr Tumor Dis NCT, Heidelberg, Germany

[8] Charite, Berlin, Germany

[9] Univ Hosp Cologne, Cologne, Germany

[10] Vrije Univ Brussel VUB, Lab Hematol & Immunol & Labor Myelomforsch, Jette, Belgium

[11] Heidelberg Univ, Inst Human Genet, Heidelberg, Germany

[12] Coordinat Ctr Clin Trials KKS, Heidelberg, Germany

[13] Univ Tubingen Hosp, Tubingen, Germany

[14] Univ Med Ctr Mainz, Mainz, Germany

[15] Univ Hosp Bonn, Bonn, Germany

[16] Helios Hosp Berlin Buch, Buch, Germany

[17] Kath Krankenhaus Hagen, Hagen, Germany

[18] Univ Hamburg Hosp, Hamburg, Germany

[19] Univ Hosp Essen, Essen, Germany

来源：

LEUKEMIA | 2021年 / 35卷 / 10期

关键词：

PERIPHERAL NEUROPATHY; DEXAMETHASONE; LENALIDOMIDE;

D O I：

10.1038/s41375-021-01298-y

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：3007 / 3011

页数：5

共 14 条

[1] Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma [J].

Arnulf, Bertrand ;

Pylypenko, Halyna ;

Groslcki, Sebastian ;

Karamanesht, Ievgenii ;

Leleu, Xavier ;

van de Velde, Helgi ;

Feng, Huaibao ;

Cakana, Andrew ;

Deraedt, William ;

Moreau, Philippe .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (12) :1925-1928

[2] Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma [J].

Attal, Michel ;

Lauwers-Cances, Valerie ;

Hulin, Cyrille ;

Leleu, Xavier ;

Caillot, Denis ;

Escoffre, Martine ;

Arnulf, Bertrand ;

Macro, Margaret ;

Belhadj, Karim ;

Garderet, Laurent ;

Roussel, Murielle ;

Payen, Catherine ;

Mathiot, Claire ;

Fermand, Jean P. ;

Meuleman, Nathalie ;

Rollet, Sandrine ;

Maglio, Michelle E. ;

Zeytoonjian, Andrea A. ;

Weller, Edie A. ;

Munshi, Nikhil ;

Anderson, Kenneth C. ;

Richardson, Paul G. ;

Facon, Thierry ;

Avet-Loiseau, Herve ;

Harousseau, Jean-Luc ;

Moreau, Philippe .

NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (14) :1311-1320

[3] Response-adapted lenalidomide maintenance in newly diagnosed myeloma: results from the phase III GMMG-MM5 trial [J].

Goldschmidt, Hartmut ;

Mai, Elias K. ;

Duerig, Jan ;

Scheid, Christof ;

Weisel, Katja C. ;

Kunz, Christina ;

Bertsch, Uta ;

Hielscher, Thomas ;

Merz, Maximilian ;

Munder, Markus ;

Lindemann, Hans-Walter ;

Huegle-Doerr, Barbara ;

Tichy, Diana ;

Giesen, Nicola ;

Hose, Dirk ;

Seckinger, Anja ;

Huhn, Stefanie ;

Luntz, Steffen ;

Jauch, Anna ;

Elmaagacli, Ahmet ;

Rabold, Bernhard ;

Fuhrmann, Stephan ;

Brossart, Peter ;

Goerner, Martin ;

Bernhard, Helga ;

Hoffmann, Martin ;

Hillengass, Jens ;

Raab, Marc S. ;

Blau, Igor W. ;

Haenel, Mathias ;

Salwender, Hans J. .

LEUKEMIA, 2020, 34 (07) :1853-1865

[4] Phase III trial of bortezomib, cyclophosphamide and dexamethasone (VCD) versus bortezomib, doxorubicin and dexamethasone (PAd) in newly diagnosed myeloma [J].

Mai, E. K. ;

Bertsch, U. ;

Duerig, J. ;

Kunz, C. ;

Haenel, M. ;

Blau, I. W. ;

Munder, M. ;

Jauch, A. ;

Schurich, B. ;

Hielscher, T. ;

Merz, M. ;

Huegle-Doerr, B. ;

Seckinger, A. ;

Hose, D. ;

Hillengass, J. ;

Raab, M. S. ;

Neben, K. ;

Lindemann, H-W ;

Zeis, M. ;

Gerecke, C. ;

Schmidt-Wolf, I. G. H. ;

Weisel, K. ;

Scheid, C. ;

Salwender, H. ;

Goldschmidt, H. .

LEUKEMIA, 2015, 29 (08) :1721-1729

[5] The clinical management of lenalidomide-based therapy in patients with newly diagnosed multiple myeloma [J].

Merz, Maximilian ;

Dechow, Tobias ;

Scheytt, Mithun ;

Schmidt, Christian ;

Hackanson, Bjoern ;

Knop, Stefan .

ANNALS OF HEMATOLOGY, 2020, 99 (08) :1709-1725

[6] Peripheral neuropathy associated with subcutaneous or intravenous bortezomib in patients with newly diagnosed myeloma treated within the GMMG MM5 phase III trial [J].

Merz, Maximilian ;

Salwender, Hans ;

Haenel, Mathias ;

Mai, Elias K. ;

Bertsch, Uta ;

Kunz, Christina ;

Hielscher, Thomas ;

Blau, Igor W. ;

Scheid, Christof ;

Hose, Dirk ;

Seckinger, Anja ;

Jauch, Anna ;

Hillengass, Jens ;

Raab, Marc S. ;

Schurich, Baerbel ;

Munder, Markus ;

Brossart, Peter ;

Gerecke, Christian ;

Lindemann, Hans-Walter ;

Zeis, Matthias ;

Weisel, Katja ;

Duerig, Jan ;

Goldschmidt, Hartmut .

HAEMATOLOGICA, 2016, 101 (12) :E485-E487

[7] Subcutaneous versus intravenous bortezomib in two different induction therapies for newly diagnosed multiple myeloma: an interim analysis from the prospective GMMG-MM5 trial [J].

Merz, Maximilian ;

Salwender, Hans ;

Haenel, Mathias ;

Mai, Elias K. ;

Bertsch, Uta ;

Kunz, Christina ;

Hielscher, Thomas ;

Blau, Igor W. ;

Scheid, Christof ;

Hose, Dirk ;

Seckinger, Anja ;

Jauch, Anna ;

Hillengass, Jens ;

Raab, Marc S. ;

Schurich, Baerbel ;

Munder, Markus ;

Schmidt-Wolf, Ingo G. H. ;

Gerecke, Christian ;

Lindemann, Hans-Walter ;

Zeis, Matthias ;

Weisel, Katja ;

Duerig, Jan ;

Goldschmidt, Hartmut .

HAEMATOLOGICA, 2015, 100 (07) :964-969

[8] Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study [J].

Moreau, Philippe ;

Attal, Michel ;

Hulin, Cyrille ;

Arnulf, Bertrand ;

Belhadj, Karim ;

Benboubker, Lotfi ;

Bene, Marie C. ;

Broijl, Annemiek ;

Caillon, Helene ;

Caillot, Denis ;

Corre, Jill ;

Delforge, Michel ;

Dejoie, Thomas ;

Doyen, Chantal ;

Facon, Thierry ;

Sonntag, Cecile ;

Fontan, Jean ;

Garderet, Laurent ;

Jie, Kon-Siong ;

Karlin, Lionel ;

Kuhnowski, Frederique ;

Lambert, Jerome ;

Leleu, Xavier ;

Lenain, Pascal ;

Macro, Margaret ;

Mathiot, Claire ;

Orsini-Piocelle, Frederique ;

Perrot, Aurore ;

Stoppa, Anne-Marie ;

van de Donk, Niels W. C. J. ;

Wuilleme, Soraya ;

Zweegman, Sonja ;

Kolb, Brigitte ;

Touzeau, Cyrille ;

Roussel, Murielle ;

Tiab, Mourad ;

Marolleau, Jean-Pierre ;

Meuleman, Nathalie ;

Vekemans, Marie-Christiane ;

Westerman, Matthijs ;

Klein, Saskia K. ;

Levin, Mark-David ;

Fermand, Jean Paul ;

Escoffre-Barbe, Martine ;

Eveillard, Jean-Richard ;

Garidi, Reda ;

Ahmadi, Tahamtan ;

Zhuang, Sen ;

Chiu, Christopher ;

Pei, Lixia .

LANCET, 2019, 394 (10192) :29-38

[9] Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study [J].

Moreau, Philippe ;

Pylypenko, Halyna ;

Grosicki, Sebastian ;

Karamanesht, Ievgenii ;

Leleu, Xavier ;

Grishunina, Maria ;

Rekhtman, Grigoriy ;

Masliak, Zvenyslava ;

Robak, Tadeusz ;

Shubina, Anna ;

Arnulf, Bertrand ;

Kropff, Martin ;

Cavet, James ;

Esseltine, Dixie-Lee ;

Feng, Huaibao ;

Girgis, Suzette ;

van de Velde, Helgi ;

Deraedt, William ;

Harousseau, Jean-Luc .

LANCET ONCOLOGY, 2011, 12 (05) :431-440

[10] Lenalidomide-induced diarrhea in patients with myeloma is caused by bile acid malabsorption that responds to treatment [J].

Pawlyn, Charlotte ;

Khan, Mohid S. ;

Muls, Ann ;

Sriskandarajah, Priya ;

Kaiser, Martin F. ;

Davies, Faith E. ;

Morgan, Gareth J. ;

Andreyev, H. Jervoise N. .

BLOOD, 2014, 124 (15) :2467-2468

← 1 2 →