Association between Body Mass Index and Clinical Outcomes of Peripheral Artery Disease after Endovascular Therapy: Data from K-VIS ELLA Registry

被引：9

作者：

Lim, Chewan ^{[1
]}

Won, Hoyoun ^{[2
]}

Ko, Young Guk ^{[3
]}

Lee, Seung Jun ^{[3
]}

Ahn, Chul Min ^{[3
]}

Min, Pil Ki ^{[4
]}

Lee, Jae Hwan ^{[5
]}

Yoon, Chang Hwan ^{[6
]}

Yu, Cheol Woong ^{[7
]}

Lee, Seung Whan ^{[8
]}

Lee, Sang Rok ^{[9
]}

Choi, Seung Hyuk ^{[10
]}

Chae, In Ho ^{[6
]}

Choi, Donghoon ^{[11
]}

机构：

[1] Hanyang Univ, Myongji Hosp, Dept Internal Med, Div Cardiol,Coll Med, Goyang, South Korea

[2] Chung Ang Univ, Chung Ang Univ Hosp, Cardiovasc & Arrhythmia Ctr, Coll Med, Seoul, South Korea

[3] Yonsei Univ, Severance Cardiovasc Hosp, Dept Internal Med, Div Cardiol,Coll Med, Seoul, South Korea

[4] Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Div Cardiol,Coll Med, Seoul, South Korea

[5] Chungnam Natl Univ Hosp, Dept Internal Med, Div Cardiol, Daejeon, South Korea

[6] Seoul Natl Univ, Div Cardiol, Bundang Hosp, Seongnam, South Korea

[7] Korea Univ, Dept Internal Med, Div Cardiol, Anam Hosp, Seoul, South Korea

[8] Univ Ulsan, Asan Med Ctr, Dept Internal Med, Div Cardiol,Coll Med, Seoul, South Korea

[9] Chonbuk Natl Univ Hosp, Dept Internal Med, Div Cardiol, Jeonju, South Korea

[10] Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Div Cardiol,Sch Med, Seoul, South Korea

[11] Yonsei Univ, Yongin Severance Hosp, Dept Internal Med, Div Cardiol,Coll Med, Yongin, South Korea

来源：

KOREAN CIRCULATION JOURNAL | 2021年 / 51卷 / 08期

关键词：

Peripheral artery disease; Body mass index; Endovascular procedure; Prognosis; COMPLICATIONS; DEFINITION; SARCOPENIA; MORTALITY; SURVIVAL; OBESITY; COHORT; RISK;

D O I：

10.4070/kcj.2021.0040

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and Objectives: Few studies have investigated the obesity paradox in clinical outcomes of peripheral artery disease (PAD). We investigated the association between body mass index (BMI) and clinical outcomes in PAD patients undergoing endovascular therapy (EVT). Methods: Patients (n=2,914) from the retrospective Korean Vascular Intervention Society Endovascular Therapy in Lower Limb Artery Disease registry were categorized according to BMI: underweight (<18.5 kg/m(2), n=204), normal weight (18.5-25 kg/m(2), n=1,818), overweight (25-30 kg/m(2), n=766), or obese (>= 30 kg/m(2), n=126). Groups were compared for major adverse cardiovascular events (MACE) and major adverse limb events (MALE). Results: The underweight and obese groups were older and had more frequent critical limb ischemia and infrapopliteal artery disease than the normal or overweight groups (all p<0.001). Hypertension and diabetes were more frequent and current smoking was less frequent in the overweight and obese groups than the underweight or normal weight groups (all p <0.001). The underweight group showed the higher rates of MACE and MALE at 3 years (17.2%, 15.7%) compared with the normal weight (10.8%, 11.7%), overweight (8.4%, 10.7%), or obese groups (8.7%, 14.3%) (log-rank p<0.001, p=0.015). In contrast, the risk of MACE was lower in the overweight than the normal weight group (adjusted hazard ratio, 0.706; 95% CI, 0.537-0.928). Conclusions: In PAD patients undergoing EVT, underweight was an independent predictor for MACE and MALE, whereas MACE risk was lower for overweight than normal weight patients.

引用

页码：696 / 707

页数：12

共 25 条

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