A thiocoumarin-based colorimetric and ratiometric fluorescent probe for Hg2+ in aqueous solution and its application in live-cell imaging

被引：48

作者：

Qin, Siyao ^{[1
]}

Chen, Bo ^{[1
]}

Huang, Jing ^{[1
]}

Han, Yifeng ^{[1
]}

机构：

[1] Zhejiang Sci Tech Univ, Key Lab Adv Text Mat & Mfg Technol, Dept Chem, Hangzhou 310018, Zhejiang, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2018年 / 42卷 / 15期

关键词：

LIVING CELLS; MERCURY IONS; SELECTIVE DETECTION; HYDROGEN-SULFIDE; HYPOCHLOROUS ACID; HIGH-SENSITIVITY; RATIONAL DESIGN; FRET SYSTEM; RHODAMINE; CHEMODOSIMETER;

D O I：

10.1039/c8nj01491d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new intramolecular charge transfer (ICT) based colorimetric and ratiometric fluorescent chemodosimeter for the detection of Hg2+ has been rationally designed and developed. The probe operates via the specific mercury-promoted desulfurization reaction of thiocoumarin to coumarin and exhibits high selectivity and sensitivity in almost pure aqueous solution (containing only 1% DMSO) with a Low detection Limit of 1.85 ppb. Furthermore, the probe was successfully used for the fluorescence imaging of Hg2+ in Live cells.

引用

页码：12766 / 12772

页数：7

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