A thiocoumarin-based colorimetric and ratiometric fluorescent probe for Hg2+ in aqueous solution and its application in live-cell imaging

被引：48

作者：

Qin, Siyao ^{[1
]}

Chen, Bo ^{[1
]}

Huang, Jing ^{[1
]}

Han, Yifeng ^{[1
]}

机构：

[1] Zhejiang Sci Tech Univ, Key Lab Adv Text Mat & Mfg Technol, Dept Chem, Hangzhou 310018, Zhejiang, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2018年 / 42卷 / 15期

关键词：

LIVING CELLS; MERCURY IONS; SELECTIVE DETECTION; HYDROGEN-SULFIDE; HYPOCHLOROUS ACID; HIGH-SENSITIVITY; RATIONAL DESIGN; FRET SYSTEM; RHODAMINE; CHEMODOSIMETER;

D O I：

10.1039/c8nj01491d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new intramolecular charge transfer (ICT) based colorimetric and ratiometric fluorescent chemodosimeter for the detection of Hg2+ has been rationally designed and developed. The probe operates via the specific mercury-promoted desulfurization reaction of thiocoumarin to coumarin and exhibits high selectivity and sensitivity in almost pure aqueous solution (containing only 1% DMSO) with a Low detection Limit of 1.85 ppb. Furthermore, the probe was successfully used for the fluorescence imaging of Hg2+ in Live cells.

引用

页码：12766 / 12772

页数：7

共 77 条

[1] Determination of mercury by anodic stripping voltammetry with a gold nanoparticle-modified glassy carbon electrode [J].

Abollino, Ornella ;

Giacomino, Agnese ;

Malandrino, Mery ;

Piscionieri, Giuseppina ;

Mentasti, Edoardo .

ELECTROANALYSIS, 2008, 20 (01) :75-83

[2]

Baum Carl R., 1999, Current Opinion in Pediatrics, V11, P265, DOI 10.1097/00008480-199906000-00018

[3] Microprobe techniques for speciation analysis and geochemical characterization of mine environments:: The mercury district of Almaden in Spain [J].

Bernaus, Anna ;

Gaona, Xavier ;

Esbri, Jose Maria ;

Higueras, Pablo ;

Falkenberg, Gerald ;

Valiente, Manuel .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2006, 40 (13) :4090-4095

[4] A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging [J].

Chen, Bo ;

Huang, Jing ;

Geng, Huiqing ;

Xuan, Lingli ;

Xu, Tengfei ;

Li, Xin ;

Han, Yifeng .

NEW JOURNAL OF CHEMISTRY, 2017, 41 (03) :1119-1123

[5] Turn-on fluorescence sensor based on the aggregation of pyrazolo[3,4-b]pyridine-based coumarin chromophores induced by Hg2+ [J].

Chen, Jianhong ;

Liu, Weimin ;

Wang, Ying ;

Zhang, Hongyan ;

Wu, Jiasheng ;

Xu, Haitao ;

Ju, Weigang ;

Wang, Pengfei .

TETRAHEDRON LETTERS, 2013, 54 (48) :6447-6449

[6] Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species [J].

Chen, Xiaoqiang ;

Wang, Fang ;

Hyun, Ji Young ;

Wei, Tingwen ;

Qiang, Jian ;

Ren, Xintong ;

Shin, Injae ;

Yoon, Juyoung .

CHEMICAL SOCIETY REVIEWS, 2016, 45 (10) :2976-3016

[7] A novel rhodamine-based fluorescent probe for the fluorogenic and chromogenic detection of Pd2+ ions and its application in live-cell imaging [J].

Chen, Yu ;

Chen, Bo ;

Han, Yifeng .

SENSORS AND ACTUATORS B-CHEMICAL, 2016, 237 :1-7

[8] A depropargylation-triggered spontaneous cyclization based fluorescent "turn-on" chemodosimeter for the detection of palladium ions and its application in live-cell imaging [J].

Chen, Yu ;

Zhang, Minmin ;

Han, Yifeng ;

Wei, Jie .

RSC ADVANCES, 2016, 6 (10) :8380-8383

[9] A highly sensitive hemicyanine-based fluorescent chemodosimeter for mercury ions in aqueous solution and living cells [J].

Chen, Yu ;

Yang, Chengyu ;

Yu, Zhenni ;

Chen, Bo ;

Han, Yifeng .

RSC ADVANCES, 2015, 5 (100) :82531-82534

[10] A Ratiometric Fluorescent Probe for Rapid Detection of Hydrogen Sulfide in Mitochondria [J].

Chen, Yuncong ;

Zhu, Chengcheng ;

Yang, Zhenghao ;

Chen, Junjie ;

He, Yafeng ;

Jiao, Yang ;

He, Weijiang ;

Qiu, Lin ;

Cen, Jiajie ;

Guo, Zijian .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (06) :1688-1691

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