Carbapenem-Resistant Enterobacterales Infection After Massive Blast Injury: Use of Cefiderocol Based Combination Therapy

被引：4

作者：

Carney, B. W. ^{[1
]}

Rizzo, J. A. ^{[2
,3
]}

Alderete, J. F. ^{[1
]}

Cindass, R. ^{[2
]}

Markelz, A. E. ^{[1
]}

Cancio, L. C. ^{[1
]}

机构：

[1] Brooke Army Med Ctr, San Antonio, TX 78234 USA

[2] US Army Inst Surg Res, San Antonio, TX 78234 USA

[3] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

来源：

MILITARY MEDICINE | 2021年 / 186卷 / 11-12期

关键词：

METALLO-BETA-LACTAMASE; BACTERIA; HEALTH;

D O I：

10.1093/milmed/usab350

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A military soldier sustained a blast injury in Afghanistan, resulting in amputations and hemipelvectomy. He developed New Delhi metallo-beta-lactamase-producing E. coli bacteremia, soft-tissue infection, and sacral osteomyelitis. These organisms are being increasingly discovered in different communities around the world. He was successfully treated with tigecycline and cefiderocol. Cefiderocol is a novel siderophore-based cephalosporine developed to treat serious infections, including those caused by carbapenem-resistant Enterobacterales.

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收藏

页码：1241 / 1245

页数：5

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