Effect of Diet and Dietary Components on the Composition of the Gut Microbiota

被引:362
作者
Beam, Ashley [1 ]
Clinger, Elizabeth [1 ,2 ]
Hao, Lei [1 ,3 ]
机构
[1] Indiana Univ Penn, Dept Food & Nutr, Indiana, PA 15705 USA
[2] Nutr Elizabeth LLC, Brookville, PA 15825 USA
[3] Indiana Univ Penn, Dept Nursing & Allied Hlth Profess, Indiana, PA 15705 USA
关键词
diet; gut microbiota; chronic disease; CHAIN FATTY-ACIDS; GLUCAGON-LIKE PEPTIDE-1; RED WINE POLYPHENOLS; FECAL MICROBIOTA; HEPATIC STEATOSIS; BACTERIA; OBESITY; PROPIONATE; HEALTH; IMPACT;
D O I
10.3390/nu13082795
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Diet and dietary components have profound effects on the composition of the gut microbiota and are among the most important contributors to the alteration in bacterial flora. This review examines the effects the "Western", "plant-based", "high-fat", "medical ketogenic", and "Mediterranean" diets have on the composition of the gut microbiota in both mice and human subjects. We show that specific dietary components that are commonly found in the "plant-based" and "Mediterranean" diet play a role in shifting the microbial composition. This review further evaluates the bacterial metabolites that are associated with diet, and their role in systemic inflammation and metabolic endotoxemia. Furthermore, the associations between diet/dietary components and altering bacterial composition, may lead to potential therapeutic targets for type II diabetes, obesity, and inflammatory diseases.
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页数:15
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