Neurological Manifestations of Dengue Infection

被引：113
作者：
Li, Guo-Hong [1 ]
Ning, Zhi-Jie [2 ]
Liu, Yi-Ming [3 ]
Li, Xiao-Hong [1 ]
机构：
[1] Shandong Univ, Jinan Cent Hosp, Dept Neurol, Jinan, Shandong, Peoples R China
[2] Jinan Infect Dis Hosp, Jinan, Shandong, Peoples R China
[3] Shandong Univ, Dept Neurol, Qilu Hosp, Jinan, Shandong, Peoples R China
来源：
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2017年 / 7卷
关键词：
dengue; neurological complications; neuropathogenesis; in children; manifestations; treatment; prevention; ACUTE DISSEMINATED ENCEPHALOMYELITIS; JAPANESE ENCEPHALITIS-VIRUS; CENTRAL-NERVOUS-SYSTEM; GUILLAIN-BARRE-SYNDROME; TRANSVERSE MYELITIS; HEMORRHAGIC-FEVER; UNUSUAL COMPLICATION; ISCHEMIC-STROKE; HYPOKALEMIC PARALYSIS; EPIDURAL HEMATOMA;
D O I：
10.3389/fcimb.2017.00449
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year > 2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis. In addition, neurological complications in children were assessed due to their atypical clinical features. Finally, dengue infection and Japanese encephalitis were compared for pathogenesis and main clinical manifestations.
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页数：13
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