A self-sufficient peroxide-driven hydroxylation biocatalyst

被引:180
作者
Cirino, PC [1 ]
Arnold, FH [1 ]
机构
[1] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
关键词
biocatalysis; cytochrome P450; enzymes; oxidation; peroxygenase;
D O I
10.1002/anie.200351434
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
42
引用
收藏
页码:3299 / 3301
页数:3
相关论文
共 40 条
[1]   The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3 [J].
Capdevila, JH ;
Wei, SZ ;
Helvig, C ;
Falck, JR ;
Belosludtsev, Y ;
Truan, G ;
GrahamLorence, SE ;
Peterson, JA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (37) :22663-22671
[2]  
Cirino PC, 2002, ADV SYNTH CATAL, V344, P932, DOI 10.1002/1615-4169(200210)344:9<932::AID-ADSC932>3.0.CO
[3]  
2-M
[4]   Protein engineering of oxygenases for biocatalysis [J].
Cirino, PC ;
Arnold, FH .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (02) :130-135
[5]   Biomimetic nonheme iron catalysts for alkane hydroxylation [J].
Costas, M ;
Chen, K ;
Que, L .
COORDINATION CHEMISTRY REVIEWS, 2000, 200 :517-544
[6]   Alkane C-H activation and functionalization with homogeneous transition metal catalysts: a century of progress-a new millennium in prospect [J].
Crabtree, RH .
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 2001, (17) :2437-2450
[7]  
de Montellano P.R. Ortiz., 1995, CYTOCHROME P450 STRU
[8]   Using proteins in their natural environment: potential and limitations of microbial whole-cell hydroxylations in applied biocatalysis [J].
Duetz, WA ;
van Beilen, JB ;
Witholt, B .
CURRENT OPINION IN BIOTECHNOLOGY, 2001, 12 (04) :419-425
[9]   Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase [J].
Glieder, A ;
Farinas, ET ;
Arnold, FH .
NATURE BIOTECHNOLOGY, 2002, 20 (11) :1135-1139
[10]   Cytochrome P450 enzymes in the generation of commercial products [J].
Guengerich, FP .
NATURE REVIEWS DRUG DISCOVERY, 2002, 1 (05) :359-366